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JAAD 2023

J Autoimmunity 2023

JACI. 2021 Apr;147(4):1402-1412

Nat Commun. 2019 Aug 8;10(1):3569

J Biomed Sci. 2022

2023年研究成果

1: Huang YH, Chen YC, Ho WM, Lee RG, Chung RH, Liu YL, Chang PY, Chang SC, Wang CW, Chung WH, Tsai SJ, Kuo PH, Lee YS, Hsiao CC. Classifying Alzheimer's disease and normal subjects using machine learning techniques and genetic-environmental features. J Formos Med Assoc. 2023 Dec 2:S0929-6646(23)00439-4. doi: 10.1016/j.jfma.2023.10.021. Epub ahead of print. PMID: 38044212. 2: Hung SI, Chu MT, Hou MM, Lee YS, Yang CK, Chu SY, Liu FY, Hsu HC, Pao SC, Teng YC, Chen CB, Chao A, Chung WH, Chang JW, Lai CH. Personalized neoantigen- based T cell therapy triggers cytotoxic lymphocytes expressing polyclonal TCR against metastatic ovarian cancer. Biomed Pharmacother. 2023 Dec 31;169:115928. doi: 10.1016/j.biopha.2023.115928. Epub 2023 Nov 26. PMID: 38011788. 3: Chen HC, Wang CW, Toh WH, Lee HE, Chung WH, Chen CB. Advancing Treatment in Bullous Pemphigoid: A Comprehensive Review of Novel Therapeutic Targets and Approaches. Clin Rev Allergy Immunol. 2023 Oct 28. doi: 10.1007/s12016-023-08973-1. Epub ahead of print. PMID: 37897588. 4: Hsueh KC, Ju PC, Hsieh YH, Su SC, Yeh CB, Lin CW. HO-3867, a curcumin analog, elicits cell apoptosis and p38-mediated caspase activation in hepatocellular carcinoma. Environ Toxicol. 2023 Oct 2. doi: 10.1002/tox.23977. Epub ahead of print. PMID: 37782689. 5: Yeh JC, Chen YT, Chou YE, Su SC, Chang LC, Chen YL, Lin CW, Yang SF. Interactive effects of CDKN2B-AS1 gene polymorphism and habitual risk factors on oral cancer. J Cell Mol Med. 2023 Nov;27(21):3395-3403. doi: 10.1111/jcmm.17966. Epub 2023 Sep 19. PMID: 37724356; PMCID: PMC10623535. 6: Wang CW, Wu MY, Chen CB, Lin WC, Wu J, Lu CW, Chen WT, Wang FY, Hui RC, Chi MH, Chiu TM, Chang YC, Lin JY, Lin YY, Tsai WT, Hung SI, Chung WH. Clinical characteristics and immune profiles of patients with immune-mediated alopecia associated with COVID-19 vaccinations. Clin Immunol. 2023 Oct;255:109737. doi: 10.1016/j.clim.2023.109737. Epub 2023 Aug 14. PMID: 37586672. 7: Chen CB, Hung WK, Wang CW, Lee CC, Hung SI, Chung WH. Advances in understanding of the pathogenesis and therapeutic implications of drug reaction with eosinophilia and systemic symptoms: an updated review. Front Med (Lausanne). 2023 Jun 29;10:1187937. doi: 10.3389/fmed.2023.1187937. PMID: 37457584; PMCID: PMC10338933. 8: Huang YW, Chung WH, Chen CB. Papuloerythroderma of Ofuji following COVID-19 vaccination. J Eur Acad Dermatol Venereol. 2023 Dec;37(12):e1360-e1362. doi: 10.1111/jdv.19294. Epub 2023 Jul 21. PMID: 37369630. 9: Wang CW, Chen CB, Lu CW, Chen WT, Hui RC, Chiu TM, Chi MH, Lin JC, Huang YH, Chang YC, Wu J, Chen KY, Lin YY, Ger TY, Lin JY, Tsai WT, Pan YJ, Chung WH. Characteristics of immune response profile in patients with immediate allergic and autoimmune urticarial reactions induced by SARS-CoV-2 vaccines. J Autoimmun. 2023 Jul;138:103054. doi: 10.1016/j.jaut.2023.103054. Epub 2023 May 15. PMID: 37245259; PMCID: PMC10183637. 10: Wung CH, Wang CW, Lai KC, Chen CB, Chen WT, Hung SI, Chung WH; Taiwan Severe Cutaneous Adverse Reaction Consortium. Current understanding of genetic associations with delayed hypersensitivity reactions induced by antibiotics and anti-osteoporotic drugs. Front Pharmacol. 2023 Apr 26;14:1183491. doi: 10.3389/fphar.2023.1183491. PMID: 37180708; PMCID: PMC10169607. 11: Wang CY, Wang CW, Chen CB, Chen WT, Chang YC, Hui RC, Chung WH. Pharmacogenomics on the Treatment Response in Patients with Psoriasis: An Updated Review. Int J Mol Sci. 2023 Apr 15;24(8):7329. doi: 10.3390/ijms24087329. PMID: 37108492; PMCID: PMC10138383. 12: Chen CB, Wang CW, Chung WH. TNF-α Blockade Inhibits Matrix Metalloproteinase 9-Mediated Collagenase Activity in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. J Invest Dermatol. 2023 Jun;143(6):881-883. doi: 10.1016/j.jid.2023.03.1652. Epub 2023 Apr 22. PMID: 37086217. 13: Lee CC, Tsai CH, Chen CH, Yeh YC, Chung WH, Chen CB. An updated review of the immunological mechanisms of keloid scars. Front Immunol. 2023 Mar 22;14:1117630. doi: 10.3389/fimmu.2023.1117630. PMID: 37033989; PMCID: PMC10075205. 14: Tseng WY, Stacey M, Lin HH. Role of Adhesion G Protein-Coupled Receptors in Immune Dysfunction and Disorder. Int J Mol Sci. 2023 Mar 13;24(6):5499. doi: 10.3390/ijms24065499. PMID: 36982575; PMCID: PMC10055975. 15: Chen YT, Lin CW, Chou YE, Su SC, Chang LC, Lee CY, Hsieh MJ, Yang SF. Potential impact of ADAM-10 genetic variants with the clinical features of oral squamous cell carcinoma. J Cell Mol Med. 2023 Apr;27(8):1144-1152. doi: 10.1111/jcmm.17728. Epub 2023 Mar 22. PMID: 36946281; PMCID: PMC10098292. 16: Huang YH, Chang LC, Chang YC, Chung WH, Yang SF, Su SC. Compositional Alteration of Gut Microbiota in Psoriasis Treated with IL-23 and IL-17 Inhibitors. Int J Mol Sci. 2023 Feb 26;24(5):4568. doi: 10.3390/ijms24054568. PMID: 36902001; PMCID: PMC10002560. 17: Su SC, Hsin CH, Lu YT, Chuang CY, Ho YT, Yeh FL, Yang SF, Lin CW. EF-24, a Curcumin Analog, Inhibits Cancer Cell Invasion in Human Nasopharyngeal Carcinoma through Transcriptional Suppression of Matrix Metalloproteinase-9 Gene Expression. Cancers (Basel). 2023 Mar 1;15(5):1552. doi: 10.3390/cancers15051552. PMID: 36900342; PMCID: PMC10000445. 18: Liu Y, Wang CW, Chen CB, Yu KH, Wu YJ, Choon SE, Chang WC, Yang F, Luo XQ, Chung WH, Zhao M, Lu QJ. DNA methylation of ITGB2 contributes to allopurinol hypersensitivity. Clin Immunol. 2023 Mar;248:109250. doi: 10.1016/j.clim.2023.109250. Epub 2023 Feb 3. PMID: 36738816. 19: Wu IW, Wu YL, Yang HY, Hsu CK, Chang LC, Twu YC, Chang YL, Chung WH, Yang CW, Hsieh WP, Su SC. Deep immune profiling of patients with renal impairment unveils distinct immunotypes associated with disease severity. Clin Kidney J. 2022 Sep 7;16(1):78-89. doi: 10.1093/ckj/sfac196. PMID: 36726440; PMCID: PMC9871851. 20: Chiu CY, Chang KC, Chang LC, Wang CJ, Chung WH, Hsieh WP, Su SC. Phenotype- specific signatures of systems-level gut microbiome associated with childhood airway allergies. Pediatr Allergy Immunol. 2023 Jan;34(1):e13905. doi: 10.1111/pai.13905. PMID: 36705037. 21: Huang YF, Su SC, Chuang HY, Chen HH, Twu YC. Histone deacetylation-regulated cell surface Siglec-7 expression promoted megakaryocytic maturation and enhanced platelet-like particle release. J Thromb Haemost. 2023 Feb;21(2):329-343. doi: 10.1016/j.jtha.2022.11.007. Epub 2022 Dec 22. PMID: 36700509. 22: Wu PC, Huang IH, Wang CW, Chung WH, Chen CB. Severe cutaneous adverse reactions after COVID-19 vaccination: A systematic review. Allergy. 2023 May;78(5):1383-1386. doi: 10.1111/all.15642. Epub 2023 Jan 27. PMID: 36627233. 23: Lu CW, Pang JS, Ko YS, Chang CJ, Wang CW, Chen WT, Chen CB, Hui RC, Hung SI, Lu LY, Lu KL, Wang CL, Wu CE, Hsu PC, Fang YF, Li SH, Ko HW, Tseng LC, Shih FY, Chen MJ, Chung WH. Zinc deficiency associated with cutaneous toxicities induced by epidermal growth factor receptor tyrosine kinase inhibitor therapy in patients with lung adenocarcinoma. J Eur Acad Dermatol Venereol. 2023 Feb;37(2):328-339. doi: 10.1111/jdv.18703. Epub 2022 Nov 16. PMID: 36366861. 24: Hung YT, Chen YW, Huang Y, Lin YJ, Chen CB, Chung WH. Acute graft-versus- host disease presenting as Stevens-Johnson syndrome and toxic epidermal necrolysis: A retrospective cohort study. J Am Acad Dermatol. 2023 Apr;88(4):792-801. doi: 10.1016/j.jaad.2022.10.035. Epub 2022 Oct 22. PMID: 36280000. 25: Hung YT, Chung WH, Chen CB. Zinc Supplementation for Epidermal Growth Factor Receptor Inhibitor-Related Periocular Dermatitis. Dermatitis. 2023 Sep- Oct;34(5):454-455. doi: 10.1097/DER.0000000000000851. Epub 2023 Jan 2. PMID: 35170522.