Research Interests
    I am always intrigued by the application of innovative sequencing technologies and experimental designs to the investigation of human diseases. My current research has largely focused on dissecting oral cancer genomics and interrogating disease-oriented microbiome. Building on this diverse research framework, together with the expertise in molecular and cell biology, my recent efforts are directed at elucidating the areca nut-related oral cancer and the host-microbiota interaction in chronic kidney disease.
Research Topics
1.Longitudinal clinical studies coupled with multi-omics analyses
2.Cancer biology
3.Human microbiome
4.Functional genomics
Research Technology
分子與細胞生物、資料探勘。

Selected Publications

1. Su SC, Galvin JE, Yang SF, Chung WH, and Chang LC. wiSDOM: a visual and statistical analytics for interrogating microbiome. Bioinformatics. 2021; 37(17):2795-2797
2.Su SC, Yeh CM, Lin CW, Hsieh YH, Chuang CY, Tang CH, Lee YC, and Yang SF. A novel melatonin-regulated lncRNA suppresses TPA-induced oral cancer cell motility through replenishing PRUNE2 expression. J Pineal Res. 2021; 71(3):e12760
3.Yang SF, Lin CW, Chuang CY, Lee YC, Chung WH, Lai HC, Chang LC, and Su SC. Host genetic associations with salivary microbiome in oral cancer. J Dental Res. 2022; 101(5):590-598
4.Wu IW, Wu YL, Yang HY, Hsu CK, Chang LC, Twu YC, Chang YL, Chung WH, Yang CW, Hsieh WP, and Su SC. Deep immune profiling of patients with renal impairment unveils distinct immunotypes associated with disease severity. Clin Kidney J. 2023; 16(1):78-89
5.Chiu CY, Chang KC, Chang LC, Wang CJ, Chung WH, Hsieh WP, and Su SC. Phenotype-specific signatures of systems-level gut microbiome associated with childhood airway allergies. Pediatr Allergy Immunol. 2023; 34(1):e13905