Composition

Objective

The pace of biomedical research has moved from genomics to proteomics. By combining basic research and clinical medicine, factors for disease diagnosis and prognosis will be more effectively discovered and even used in the development of new therapeutic drugs. However, regardless of the methodology, there must be sufficient and good-quality samples to verify its findings. For a long time, Chang Gung Memorial Hospital and Linkou General Hospital have been adhering to the best service to take care of patients, thus attracting a large number of patients for consultation. If the samples taken from patients after consultation can be legally and properly managed and used, they will be the hospital's most valuable asset. On the other hand, many researchers in the hospital have a strong interest in the development, diagnosis, treatment, and prognosis of human diseases. If you need to collect samples yourself before starting research, access to samples will be an insurmountable problem. Therefore, on January 1, 1995, the hospital established the "Tissue Bank" in the form of a hospital plan.

Goal

The research specimen processing laboratory integrates the "Tumor Bank" of pairs of fresh-frozen tumor and non-tumor tissues and serum collected by the Department of Surgery since 1985 and has reached more than 80,000 pairs so far, as well as tissue paraffins preserved by the Department of Anatomy and Pathology since the 1970s. Blocks and tissue slices are provided to researchers for application. Each fresh tissue is diagnosed and classified by the pathology department, and the representative tissue will be immediately frozen and stored in a -80°C refrigerator. Its basic information (including gender, age, medical record number, and pathological diagnosis) will be stored in the database for easy querying. The research specimen processing laboratory provides human tissue samples to researchers in the hospital, and the organization must first obtain the permission of the human experiment committee and the consent of the patients. The research specimen processing laboratory will provide existing resources to accelerate integrated research and will document the tissues used by researchers and their research topics as a basis for integrating related research and making the hospital's research results more clinically meaningful.