論文發表
The papers we have published under this grant are listed as follows.
1. Lin NC, Shih YH, Chiu KC, Li PJ, Yang HW, Lan WC, Hsia SM, Wang TH, Shieh TM. Association of rs9679162 Genetic Polymorphism and Aberrant Expression of Polypeptide N-Acetylgalactosaminyltransferase 14 (GALNT14) in Head and Neck Cancer. Cancers (Basel). 2022 Aug 30;14(17):4217. doi: 10.3390/cancers14174217.
2. Lin NC, Hsia SM, Wang TH, Li PJ, Tseng YH, Chiu KC, Tu HF, Shih YH, Shieh TM. The relation between NEAT1 expression level and survival rate in patients with oral squamous cell carcinoma. J Dent Sci. 2022 Jan;17(1):361-367. doi: 10.1016/j.jds.2021.09.018. Epub 2021 Sep 24.
3. Chuang WY, Yu WH, Lee YC, Zhang QY, Chang H, Shih LY, Yeh CJ, Lin SM, Chang SH, Ueng SH, Wang TH, Hsueh C, Kuo CF, Chuang SS, Yeh CY. Deep Learning-Based Nuclear Morphometry Reveals an Independent Prognostic Factor in Mantle Cell Lymphoma. Am J Pathol. 2022 Sep 21:S0002-9440(22)00282-6. doi: 10.1016/j.ajpath.2022.08.006. Online ahead of print.
4. Wang TH, Leu YL, Chen CC, Li HJ, Yang SC, Huang KY, Chen CY. Psorachromene induces apoptosis and suppresses tumor growth in NSCLC cells harboring EGFR L858R/T790M/C797S. Phytother Res. 2022 May;36(5):2116-2126. doi: 10.1002/ptr.7432. Epub 2022 Mar 1.
5. Shih YH, Hsia SM, Chiu KC, Wang TH, Chien CY, Li PJ, Kuo YH, Shieh TM. In Vitro Antimicrobial Potential of CAPE and Caffeamide Derivatives against Oral Microbes. Int J Mol Sci. 2022 Apr 7;23(8):4099. doi: 10.3390/ijms23084099.
6. Wang TH, Tseng WC, Leu YL, Chen CY, Lee WC, Chi YC, Cheng SF, Lai CY, Kuo CH, Yang SL, Yang SH, Shen JJ, Feng CH, Wu CC, Hwang TL, Wang CJ, Wang SH, Chen CC.The flavonoid corylin exhibits lifespan extension properties in mouse. Nat Commun. 2022 Mar 9;13(1):1238. doi: 10.1038/s41467-022-28908-2.
7. Kuo YT, Liao CK, Chen TC, Lai CC, Chiang SF, Chiang JM. A high density of PD-L1-expressing immune cells is significantly correlated with favorable disease free survival in nonmetastatic colorectal cancer. Medicine (Baltimore). 2022 Jan 21;101(3):e28573. doi: 10.1097/MD.0000000000028573.
8. Huang SF, Chen TC, Hsu JT, Tsai CY, Liu KH, Yeh CN, Yeh TS. Lymph node micrometastasis of poorly differentiated node-negative gastric cancer risks a worse-than-expected survival outcome under standard management algorithm. Eur J Surg Oncol. 2022 Apr;48(4):783-788. doi: 10.1016/j.ejso.2021.11.117. Epub 2021 Nov 19.
9. Huang SC, Chen KH, Ng KF, Lin IC, Chao YC, Yeh TS, Chuang HC, Chen TC. Dedifferentiation-like tubular and solid carcinoma of the stomach shows phenotypic divergence and association with deficient SWI/SNF complex. Virchows Arch. 2022 Apr;480(4):771-781. doi: 10.1007/s00428-022-03288-6. Epub 2022 Feb 4.
10. Cheng JS, Chen TC, Chen TD, Ku HP, Huang SW, Wu TS, Chien RN, Chang ML. Association between breast cancer and hepatitis C: A joint study of hospitalized patients and nationwide cohorts. Transl Res. 2022 Jul;245:117-129. doi: 10.1016/j.trsl.2022.02.009. Epub 2022 Mar 5.
11. Chen KH, Huang HY, Chen TC, Liu YJ, Lin IC, Ng KF, Chuang HC, Huang SC. A clinicopathological reappraisal of orbital vascular malformations and distinctive GJA4 mutation in cavernous venous malformations. Hum Pathol. 2022 Oct 6:S0046-8177(22)00241-6. doi: 10.1016/j.humpath.2022.10.002. Online ahead of print.
12. Wang HS, Liu CY, Hsu SC, Huang SC, Hung TH, Ng KF, Chen TC. A Single-Institute Experience with C-ros Oncogene 1 Translocation in Non-Small Cell Lung Cancers in Taiwan. Int J Mol Sci. 2022 May 21;23(10):5789. doi: 10.3390/ijms23105789.
13. Tsai CY, Wang SY, Chan KM, Lee WC, Chen TC, Yeh TS, Jan YY, Yeh CN. Hepatectomy or/with Metastatectomy for Recurrent Intrahepatic Cholangiocarcinoma: Of Promise for Selected Patients. J Pers Med. 2022 Mar 29;12(4):540. doi: 10.3390/jpm12040540.
14. Huang SC, Chen CC, Lan J, Hsieh TY, Chuang HC, Chien MY, Ou TS, Chen KH, Wu RC, Liu YJ, Cheng CT, Huang YJ, Tao LW, Hwu AF, Lin IC, Hung SH, Yeh CY, Chen TC. Deep neural network trained on gigapixel images improves lymph node metastasis detection in clinical settings. Nat Commun. 2022 Jun 10;13(1):3347. doi: 10.1038/s41467-022-30746-1.
15. Lin HH, Ng KF, Chen TC, Tseng WY. Ligands and Beyond: Mechanosensitive Adhesion GPCRs. Pharmaceuticals (Basel). 2022 Feb 11;15(2):219. doi: 10.3390/ph15020219.Chen CC, Chen CY, Cheng SF, Shieh TM, Leu YL, Chuang WY, Liu KT, Ueng SH, Shih YH, Chou LF, Wang TH. Hydroxygenkwanin Increases the Sensitivity of Liver Cancer Cells to Chemotherapy by Inhibiting DNA Damage Response in Mouse Xenograft Models. Int J Mol Sci. 2021 Sep 9;22(18):9766. doi: 10.3390/ijms22189766.
16. Peng TY, Lin DJ, Mine Y, Tasi CY, Li PJ, Shih YH, Chiu KC, Wang TH, Hsia SM, Shieh TM. Biofilm Formation on the Surface of (Poly)Ether-Ether-Ketone and In Vitro Antimicrobial Efficacy of Photodynamic Therapy on Peri-Implant Mucositis. Polymers (Basel). 2021 Mar 18;13(6):940. doi: 10.3390/polym13060940.
17. Peng TY, Shih YH, Hsia SM, Wang TH, Li PJ, Lin DJ, Sun KT, Chiu KC, Shieh TM. In Vitro Assessment of the Cell Metabolic Activity, Cytotoxicity, Cell Attachment, and Inflammatory Reaction of Human Oral Fibroblasts on Polyetheretherketone (PEEK) Implant-Abutment. Polymers (Basel). 2021 Sep 3;13(17):2995. doi: 10.3390/polym13172995.
18. Huang KY, Wang TH, Chen CC, Leu YL, Li HJ, Jhong CL, Chen CY. Growth Suppression in Lung Cancer Cells Harboring EGFR-C797S Mutation by Quercetin. Biomolecules. 2021 Aug 25;11(9):1271. doi: 10.3390/biom11091271.
19. Wang TH, Chen CC, Leu YL, Lee YS, Lian JH, Hsieh HL, Chen CY. Palbociclib induces DNA damage and inhibits DNA repair to induce cellular senescence and apoptosis in oral squamous cell carcinoma. J Formos Med Assoc. 2021 Sep;120(9):1695-1705. doi: 10.1016/j.jfma.2020.12.009. Epub 2020 Dec 18.
20. Shih YH, Chiu KC, Wang TH, Lan WC, Tsai BH, Wu LJ, Hsia SM, Shieh TM. Effects of melatonin to arecoline-induced reactive oxygen species production and DNA damage in oral squamous cell carcinoma. J Formos Med Assoc. 2021 Jan;120(1 Pt 3):668-678. doi: 10.1016/j.jfma.2020.07.037. Epub 2020 Aug 13.
21. Chiu KC, Shih YH, Wang TH, Lan WC, Li PJ, Jhuang HS, Hsia SM, Shen YW, Yuan-Chien Chen M, Shieh TM. In vitro antimicrobial and antipro-inflammation potential of honokiol and magnolol against oral pathogens and macrophages. J Formos Med Assoc. 2021 Feb;120(2):827-837. doi: 10.1016/j.jfma.2020.09.002. Epub 2020 Sep 23.
22. Kang CJ, Tsai CY, Lee LY, Lin CY, Yang LY, Cheng NM, Hsueh C, Fan KH, Wang HM, Hsieh CH, Ng SH, Yeh CH, Lin CH, Tsao CK, Fang TJ, Huang SF, Lee LA, Fang KH, Wang YC, Lin WN, Hsin LJ, Yen TC, Liao CT. Prognostic stratification of patients with AJCC 2018 pStage IVB oral cavity cancer: Should pT4b and pN3 disease be reclassified? Oral Oncol. 2021 Aug;119:105371. doi: 10.1016/j.oraloncology.2021.105371. Epub 2021 Jun 24.
23. Lee LY, Lin CY, Cheng NM, Tsai CY, Hsueh C, Fan KH, Wang HM, Hsieh CH, Ng SH, Yeh CH, Lin CH, Tsao CK, Fang TJ, Huang SF, Lee LA, Kang CJ, Fang KH, Wang YC, Lin WN, Hsin LJ, Yen TC, Liao CT. Poor tumor differentiation is an independent adverse prognostic variable in patients with locally advanced oral cavity cancer--Comparison with pathological risk factors according to the NCCN guidelines. Cancer Med. 2021 Oct;10(19):6627-6641. doi: 10.1002/cam4.4195. Epub 2021 Sep 17.
24. Lin CY, Lee LY, Cheng NM, Lee SR, Tsai CY, Hsueh C, Fan KH, Wang HM, Hsieh CH, Ng SH, Yeh CH, Lin CH, Tsao CK, Fang TJ, Huang SF, Lee LA, Kang CJ, Fang KH, Wang YC, Lin WN, Hsin LJ, Yen TC, Liao CT. cN+pN0 disease does not portend a less favorable prognosis compared with cN0pN0 in patients with resected oral cavity squamous cell carcinoma. Cancer Med. 2021 Oct;10(20):6947-6958. doi: 10.1002/cam4.4187. Epub 2021 Sep 23.
25. Tsai CY, Lee SR, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, Hsieh CH, Ng SH, Yeh CH, Lin CH, Tsao CK, Fang TJ, Huang SF, Lee LA, Kang CJ, Fang KH, Wang YC, Lin WN, Hsin LJ, Yen TC, Cheng NM, Wen YW, Liao CT. Clinical outcomes of Taiwanese patients with resected squamous cell carcinoma of the upper and lower gum. Oral Oncol. 2021 Jul;118:105334. doi: 10.1016/j.oraloncology.2021.105334. Epub 2021 May 19.
26. Chuang WY, Chen CC, Yu WH, Yeh CJ, Chang SH, Ueng SH, Wang TH, Hsueh C, Kuo CF, Yeh CY. Identification of nodal micrometastasis in colorectal cancer using deep learning on annotation-free whole-slide images. Mod Pathol. 2021 Oct;34(10):1901-1911. doi: 10.1038/s41379-021-00838-2. Epub 2021 Jun 8.
27. Chen SH, Du CJ, Lai JY, Chang TY, Yang CP, Hung IJ, Jaing TH, Ming YC, Hsueh C. Malignant sacrococcygeal germ cell tumors in children in Taiwan: A retrospective single-center case series. Medicine (Baltimore). 2021 Jan 29;100(4):e24323. doi: 10.1097/MD.0000000000024323.
28. Yu CC, Cheung YC, Hsueh C, Chen SC. Predictors of Sentinel Lymph Node Metastasis in Postoperatively Upgraded Invasive Breast Carcinoma Patients. Cancers (Basel). 2021 Aug 14;13(16):4099. doi: 10.3390/cancers13164099.
29. Lu YL, Chen ST, Ho TY, Chan WH, Wong RJ, Hsueh C, Lin SF. Primary lung cancer with radioiodine avidity: A thyroid cancer cohort study. World J Clin Cases. 2021 Jan 6;9(1):71-80. doi: 10.12998/wjcc.v9.i1.71.
30. Chen JC, Hsueh C. Apple-core lesion of the terminal ileum in a child with chronic constipation. Arch Dis Child. 2021 Apr 27:archdischild-2021-321935. doi: 10.1136/archdischild-2021-321935. Online ahead of print.
31. Yeh PJ, Chen CC, Chao HC, Lai JY, Hsueh C, Wang CJ, Lai MW. High initial bowel resection rate and very-early-onset inflammatory bowel disease - A challenge in a low-prevalence area. J Formos Med Assoc. 2021 Jan;120(1 Pt 3):720-727. doi: 10.1016/j.jfma.2020.08.006. Epub 2020 Aug 17.
32. Liao CT, Hsieh CH, Fan WL, Ng SH, Cheng NM, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, Lin CH, Tsao CK, Kang CJ, Fang TJ, Huang SF, Chang KP, Lee LA, Fang KH, Wang YC, Yang LY, Yen TC. A combined analysis of maximum standardized uptake value on FDG-PET, genetic markers, and clinicopathological risk factors in the prognostic stratification of patients with resected oral cavity squamous cell carcinoma. Eur J Nucl Med Mol Imaging. 2020 Jan;47(1):84-93. doi: 10.1007/s00259-019-04453-x. Epub 2019 Aug 6.
33. Lin CY, Fan KH, Lee LY, Hsueh C, Yang LY, Ng SH, Wang HM, Hsieh CH, Lin CH, Tsao CK, Kang CJ, Fang TJ, Lee LA, Huang SF, Chang KP, Yen TC, Tay ZY, Wen YW, Lee SR, Liao CT. Precision Adjuvant Therapy Based on Detailed Pathologic Risk Factors for Resected Oral Cavity Squamous Cell Carcinoma: Long-Term Outcome Comparison of CGMH and NCCN Guidelines. Int J Radiat Oncol Biol Phys. 2020 Apr 1;106(5):916-925. doi: 10.1016/j.ijrobp.2019.08.058. Epub 2019 Sep 6.
34. Chen YT, Ou Yang WT, Juang HH, Chen CL, Chen HW, Tsui KH, Chang YH, Tsai CH, Hsueh C, Liao WC. Proteomic characterization of arsenic and cadmium exposure in bladder cells. Rapid Commun Mass Spectrom. 2020 Apr;34 Suppl 1:e8578. doi: 10.1002/rcm.8578. Epub 2020 Feb 8.
35. Chen CY, Fang JY, Chen CC, Chuang WY, Leu YL, Ueng SH, Wei LS, Cheng SF, Hsueh C, Wang TH. 2-O-Methylmagnolol, a Magnolol Derivative, Suppresses Hepatocellular Carcinoma Progression via Inhibiting Class I Histone Deacetylase Expression. Front Oncol. 2020 Aug 11;10:1319. doi: 10.3389/fonc.2020.01319. eCollection 2020.
36. Tsai CY, Chen ST, Hsueh C, Lin YS, Lin JD. Long-term therapeutic outcomes of papillary thyroid carcinoma with concomitant hyperparathyroidism: A single center case-control study. Biomed J. 2020 Feb;43(1):53-61. doi: 10.1016/j.bj.2019.05.010. Epub 2020 Feb 27.
37. Yeh PJ, Chen CC, Chao HC, Lai JY, Hsueh C, Wang CJ, Lai MW. High initial bowel resection rate and very-early-onset inflammatory bowel disease - A challenge in a low-prevalence area. J Formos Med Assoc. 2020 Aug 17:S0929-6646(20)30360-0. doi: 10.1016/j.jfma.2020.08.006. Online ahead of print.
38. Chen CY, Chen CC, Chuang WY, Leu YL, Ueng SH, Hsueh C, Yeh CT, Wang TH. Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer Cells. Front Oncol. 2020 Feb 25;10:216. doi: 10.3389/fonc.2020.00216. eCollection 2020.
39. Wang TH, Wu CC, Huang KY, Chuang WY, Hsueh C, Li HJ, Chen CY. Profiling of subcellular EGFR interactome reveals hnRNP A3 modulates nuclear EGFR localization. Oncogenesis. 2020 Apr 22;9(4):40. doi: 10.1038/s41389-020-0225-0.
40. Chuang WY, Chang ST, Yuan CT, Chang GJ, Chang H, Yeh CJ, Ueng SH, Kao HW, Wang TH, Wan YL, Shih LY, Chuang SS, Hsueh C. Identification of CD5/Cyclin D1 Double-negative Pleomorphic Mantle Cell Lymphoma: A Clinicopathologic, Genetic, and Gene Expression Study. Am J Surg Pathol. 2020 Feb;44(2):232-240. doi: 10.1097/PAS.0000000000001390.
41. Chuang WY, Chang SH, Yu WH, Yang CK, Yeh CJ, Ueng SH, Liu YJ, Chen TD, Chen KH, Hsieh YY, Hsia Y, Wang TH, Hsueh C, Kuo CF, Yeh CY. Successful Identification of Nasopharyngeal Carcinoma in Nasopharyngeal Biopsies Using Deep Learning. Cancers (Basel). 2020 Feb 22;12(2):507. doi: 10.3390/cancers12020507.
42. Chiu KC, Shih YH, Wang TH, Lan WC, Li PJ, Jhuang HS, Hsia SM, Shen YW, Yuan-Chien Chen M, Shieh TM. In vitro antimicrobial and antipro-inflammation potential of honokiol and magnolol against oral pathogens and macrophages. J Formos Med Assoc. 2020 Sep 23:S0929-6646(20)30425-3. doi: 10.1016/j.jfma.2020.09.002. Online ahead of print.
43. Lu CS, Lin CW, Chang YH, Chen HY, Chung WC, Lai WY, Ho CC, Wang TH, Chen CY, Yeh CL, Wu S, Wang SP, Yang PC. Antimetabolite pemetrexed primes a favorable tumor microenvironment for immune checkpoint blockade therapy. J Immunother Cancer. 2020 Nov;8(2):e001392. doi: 10.1136/jitc-2020-001392.
44. Leu YL, Wang TH, Wu CC, Huang KY, Jiang YW, Hsu YC, Chen CY. Hydroxygenkwanin Suppresses Non-Small Cell Lung Cancer Progression by Enhancing EGFR Degradation. Molecules. 2020 Feb 19;25(4):941. doi: 10.3390/molecules25040941.
45. Shih YH, Chiu KC, Wang TH, Lan WC, Tsai BH, Wu LJ, Hsia SM, Shieh TM. Effects of melatonin to arecoline-induced reactive oxygen species production and DNA damage in oral squamous cell carcinoma. J Formos Med Assoc. 2020 Aug 13:S0929-6646(20)30349-1. doi: 10.1016/j.jfma.2020.07.037. Online
46. Chi CP, Hou CW, Wu YY, Wang TH, Yu SH. Night time resistance exercise alters muscular IL-6-related protein signaling, but not muscle growth after 10 weeks of resistance training in male rats. Gen Physiol Biophys. 2020 Jan;39(1):89-98. doi: 10.4149/gpb_2019047.
47. Lin PH, Chiang YF, Shieh TM, Chen HY, Shih CK, Wang TH, Wang KL, Huang TC, Hong YH, Li SC, Hsia SM. Dietary Compound Isoliquiritigenin, an Antioxidant from Licorice, Suppresses Triple-Negative Breast Tumor Growth via Apoptotic Death Program Activation in Cell and Xenograft Animal Models. Antioxidants (Basel). 2020 Mar 10;9(3):228. doi: 10.3390/antiox9030228.
48. Chuang WY, Chang ST, Yuan CT, Chang GJ, Chang H, Yeh CJ, Ueng SH, Kao HW, Wang TH, Wan YL, Shih LY, Chuang SS, Hsueh C. Identification of CD5/Cyclin D1 Double-negative Pleomorphic Mantle Cell Lymphoma: A Clinicopathologic, Genetic, and Gene Expression Study. Am J Surg Pathol. 2020 Feb;44(2):232-240. doi: 10.1097/PAS.0000000000001390.
49. Chen YT, Ou Yang WT, Juang HH, Chen CL, Chen HW, Tsui KH, Chang YH, Tsai CH, Hsueh C, Liao WC. Proteomic characterization of arsenic and cadmium exposure in bladder cells. Rapid Commun Mass Spectrom. 2019 Sep 9. doi: 10.1002/rcm.8578.
50. Lin CY, Fan KH, Lee LY, Hsueh C, Yang LY, Ng SH, Wang HM, Hsieh CH, Lin CH, Tsao CK, Kang CJ, Fang TJ, Lee LA, Huang SF, Chang KP, Yen TC, Tay ZY, Wen YW, Lee SR, Liao CT. Precision Adjuvant Therapy Based on Detailed Pathological Risk Factors for Resected Oral Cavity Squamous Cell Carcinoma: Long Term Outcome Comparison of CGMH and NCCN Guidelines. Int J Radiat Oncol Biol Phys. 2019 Sep 6. pii: S0360-3016(19)33747-2. doi: 10.1016/j.ijrobp.2019.08.058.
51. Liao CT, Hsieh CH, Fan WL, Ng SH, Cheng NM, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, Lin CH, Tsao CK, Kang CJ, Fang TJ, Huang SF, Chang KP, Lee LA, Fang KH, Wang YC, Yang LY, Yen TC. A combined analysis of maximum standardized uptake value on FDG-PET, genetic markers, and clinicopathological risk factors in the prognostic stratification of patients with resected oral cavity squamous cell carcinoma. Eur J Nucl Med Mol Imaging. 2020 Jan;47(1):84-93. doi: 10.1007/s00259-019-04453-x. Epub 2019 Aug 6.
52. Liao CT, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, Hsieh CH, Ng SH, Lin CH, Tsao CK, Kang CJ, Fang TJ, Huang SF, Chang KP, Lee LA, Fang KH, Wang YC, Lin WN, Hsin LJ, Yang LY, Yen TC. Tumor Depth of Invasion (Tumor > 4 cm/Depth > 10 mm and Depth > 20 mm) and Through Cortex/Skin Invasion are Both Valid Criteria for Classifying Tumors as pT4a in AJCC 2018 Oral Cavity Cancer Staging System. Ann Surg Oncol. 2019 Oct;26(11):3663-3672. doi: 10.1245/s10434-019-07576-5. Epub 2019 Jul 1.
53. Ng SC, Huang BY, Kuo SF, Hsueh C, Chiang KC, Chen CH, Lin JD. Diagnostic pitfalls and therapeutic outcomes of the macrofollicular variant of papillary thyroid carcinoma. Biomed J. 2019 Feb;42(1):59-65. doi: 10.1016/j.bj.2018.12.006. Epub 2019 Mar 20.
54. Chou LF, Chen CY, Yang WH, Chen CC, Chang JL, Leu YL, Liou MJ, Wang TH. Suppression of Hepatocellular Carcinoma Progression through FOXM1 and EMT Inhibition via Hydroxygenkwanin-Induced miR-320a Expression. Biomolecules. 2019 Dec 21;10(1). pii: E20. doi: 10.3390/biom10010020.
55. Wang TH, Leu YL, Chen CC, Shieh TM, Lian JH, Chen CY. Psorachromene Suppresses Oral Squamous Cell Carcinoma Progression by Inhibiting Long Non-coding RNA GAS5 Mediated Epithelial-Mesenchymal Transition. Front Oncol. 2019 Nov 5;9:1168. doi: 10.3389/fonc.2019.01168. eCollection 2019.
56. Kuo CH, Leu YL, Wang TH, Tseng WC, Feng CH, Wang SH, Chen CC. A novel DNA repair inhibitor, diallyl disulfide (DADS), impairs DNA resection during DNA double-strand break repair by reducing Sae2 and Exo1 levels. DNA Repair (Amst). 2019 Oct;82:102690. doi:10.1016/j.dnarep.2019.102690. Epub 2019 Aug 24.
57. Wang TH, Chen CC, Huang KY, Shih YM, Chen CY. High levels of EGFR prevent sulforaphane-induced reactive oxygen species-mediated apoptosis in non-small-cell lung cancer cells. Phytomedicine. 2019 Nov;64:152926. doi: 10.1016/j.phymed.2019.152926. Epub 2019 Apr 13.
58. Tu MG, Sun KT, Wang TH, He YZ, Hsia SM, Tsai BH, Shih YH, Shieh TM. Effects of mineral trioxide aggregate and bioceramics on macrophage differentiation and polarization in vitro. J Formos Med Assoc. 2019 Oct;118(10):1458-1465. doi: 10.1016/j.jfma.2019.07.010. Epub 2019 Jul 26.
59. Shih YH, Wang TH, Shieh TM, Tseng YH. Oral Submucous Fibrosis: A Review on Etiopathogenesis, Diagnosis, and Therapy. Int J Mol Sci. 2019 Jun 16;20(12). pii: E2940. doi: 10.3390/ijms20122940. Review.
60. Wang TH, Chen CC, Hsiao YC, Lin YH, Pi WC, Huang PR, Wang TV, Chen CY. Heterogeneous Nuclear Ribonucleoproteins A1 and A2 Function in Telomerase-Dependent Maintenance of Telomeres. Cancers (Basel). 2019 Mar 8;11(3). pii: E334. doi: 10.3390/cancers11030334.
61. 2-O-Methylmagnolol Induces Apoptosis and Inhibits IL-6/STAT3 Signaling in Oral Squamous Cell Carcinoma. Wang TH, Fang JY, Wu SJ, Liu YW, Chan CW, Chuang SY, Chen CY. Cell Physiol Biochem. 2018;50(3):883-892. doi: 10.1159/000494474. Epub 2018 Oct 24.
62. Activity of roniciclib in medullary thyroid cancer. Lin SF, Lin JD, Hsueh C, Chou TC, Wong RJ. Oncotarget. 2018 Jun 15;9(46):28030-28041. doi: 10.18632/oncotarget.25555. eCollection 2018 Jun 15.PMID: 29963260
63. Application of ribonucleoside vanadyl complex (RVC) for developing a multifunctional tissue preservative solution. Shieh TM, Chen CY, Hsueh C, Yu CC, Chen CC, Wang TH. PLoS One. 2018 Mar 14;13(3):e0194393. doi: 10.1371/journal.pone.0194393. eCollection 2018.
64. Corylin increases the sensitivity of hepatocellular carcinoma cells to chemotherapy through long noncoding RNA RAD51-AS1-mediated inhibition of DNA repair. Chen CC, Chen CY, Ueng SH, Hsueh C, Yeh CT, Ho JY, Chou LF, Wang TH. Cell Death Dis. 2018 May 1;9(5):543. doi: 10.1038/s41419-018-0575-0.
65. Corylin Suppresses Hepatocellular Carcinoma Progression via the Inhibition of Epithelial-Mesenchymal Transition, Mediated by Long Noncoding RNA GAS5. Chen CY, Chen CC, Shieh TM, Hsueh C, Wang SH, Leu YL, Lian JH, Wang TH. Int J Mol Sci. 2018 Jan 27;19(2). pii: E380. doi: 10.3390/ijms19020380.
66. Cytoplasmic LIF reprograms invasive mode to enhance NPC dissemination through modulating YAP1-FAK/PXN signaling.
67. Liu SC, Hsu T, Chang YS, Chung AK, Jiang SS, OuYang CN, Yuh CH, Hsueh C, Liu YP, Tsang NM. Nat Commun. 2018 Nov 30;9(1):5105. doi: 10.1038/s41467-018-07660-6. PMID: 30504771
68. Differentiation of the Follicular Variant of Papillary Thyroid Carcinoma From Classic Papillary Thyroid Carcinoma: An Ultrasound Analysis and Complement to Fine-Needle Aspiration Cytology. Ng SC, Kuo SF, Hua CC, Huang BY, Chiang KC, Chu YY, Hsueh C, Lin JD. J Ultrasound Med. 2018 Mar;37(3):667-674. doi: 10.1002/jum.14377. Epub 2017 Sep 7. PMID: 28880405
69. Integrated analysis of fine-needle-aspiration cystic fluid proteome, cancer cell secretome, and public transcriptome datasets for papillary thyroid cancer biomarker discovery. Wu CC, Lin JD, Chen JT, Chang CM, Weng HF, Hsueh C, Chien HP, Yu JS. Oncotarget. 2018 Jan 4;9(15):12079-12100. doi: 10.18632/oncotarget.23951. eCollection 2018 Feb 23. PMID: 29552294
70. Low PD-L1 Expression Strongly Correlates with Local Recurrence in Epstein-Barr Virus-Positive Nasopharyngeal Carcinoma after Radiation-Based Therapy. Liu YJ, Tsang NM, Hsueh C, Yeh CJ, Ueng SH, Wang TH, Chuang WY. Cancers (Basel). 2018 Oct 9;10(10). pii: E374. doi: 10.3390/cancers10100374.
71. Melatonin Inhibits the Progression of Hepatocellular Carcinoma through MicroRNA Let7i-3p Mediated RAF1 Reduction. Wang TH, Hsueh C, Chen CC, Li WS, Yeh CT, Lian JH, Chang JL, Chen CY. Int J Mol Sci. 2018 Sep 10;19(9). pii: E2687. doi: 10.3390/ijms19092687.
72. Melatonin Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Through Long Non-Coding RNA RAD51-AS1-Mediated Suppression of DNA Repair. Chen CC, Chen CY, Wang SH, Yeh CT, Su SC, Ueng SH, Chuang WY, Hsueh C, Wang TH. Cancers (Basel). 2018 Sep 10;10(9). pii: E320. doi: 10.3390/cancers10090320.
73. Pathological risk factors stratification in pN3b oral cavity squamous cell carcinoma: Focus on the number of positive nodes and extranodal extension. Liao CT, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, Hsieh CH, Ng SH, Lin CH, Tsao CK, Kang CJ, Fang TJ, Huang SF, Chang KP, Yang LY, Yen TC. Oral Oncol. 2018 Nov;86:188-194. doi: 10.1016/j.oraloncology.2018.09.021. Epub 2018 Sep 28. PMID: 30409299
74. Potent effects of roniciclib alone and with sorafenib against well-differentiated thyroid cancer. Lin SF, Lin JD, Hsueh C, Chou TC, Wong RJ. Endocr Relat Cancer. 2018 Oct;25(10):853-864. doi: 10.1530/ERC-18-0150. Epub 2018 Jun 12. PMID: 29895526
75. Systematic verification of bladder cancer-associated tissue protein biomarker candidates in clinical urine specimens. Tsai CH, Chen YT, Chang YH, Hsueh C, Liu CY, Chang YS, Chen CL, Yu JS. Oncotarget. 2018 Jul 20;9(56):30731-30747. doi: 10.18632/oncotarget.24578. eCollection 2018 Jul 20. PMID: 30112103
76. β-Nitrostyrene derivatives attenuate LPS-mediated acute lung injury via the inhibition of neutrophil-platelet interactions and NET release. Chang YW, Tseng CP, Lee CH, Hwang TL, Chen YL, Su MT, Chong KY, Lan YW, Wu CC, Chen KJ, Lu FH, Liao HR, Hsueh C, Hsieh PW. Am J Physiol Lung Cell Mol Physiol. 2018 Apr 1;314(4):L654-L669. doi: 10.1152/ajplung.00501.2016. Epub 2018 Jan 11. PMID: 29351433
77. Hsu JT, Chen TD, Chuang HC, Huang SC, Le PH, Chen TH, Lin CJ, Yeh TS. Vascular endothelial growth factor expression is an independent poor prognostic factor for human epidermal growth factor receptor 2 positive gastric cancer. J Surg Res. 2017 Feb;208:40-50. doi: 10.1016/j.jss.2016.09.004.
78. Hsu JT, Liao JA, Chuang HC, Chen TD, Chen TH, Kuo CJ, Lin CJ, Chou WC, Yeh TS, Jan YY. Palliative gastrectomy is beneficial in selected cases of metastatic gastric cancer. BMC Palliat Care. 2017 Mar 14;16(1):19. doi: 10.1186/s12904-017-0192-1.
79. Wei KC, Chen CY, Feng LY, Huang WT, Chen CH, Hsu PW, Wang K, Hood LE, Chen LY. The rs16906252:C>T SNP is not associated with increased overall survival or temozolomide response in a Han-Chinese glioma cohort. PLoS One. 2017 Jun 2;12(6):e0178842. doi: 10.1371/journal.pone.0178842.
80. Chao A, Lin CY, Chao AN, Tsai CL, Chen MY, Lee LY, Chang TC, Wang TH, Lai CH, Wang HS. Lysine-specific demethylase 1 (LSD1) destabilizes p62 and inhibits autophagy in gynecologic malignancies. Oncotarget. 2017 Aug 10;8(43):74434-74450. doi: 10.18632/oncotarget.20158.
81. Huang CC, Chang PH, Wu PW, Wang CH, Fu CH, Huang CC, Tseng HJ, Lee TJ. Impact of nasal symptoms on the evaluation of asthma control. Medicine (Baltimore). 2017 Feb;96(8):e6147. doi: 10.1097/MD.0000000000006147.
82. Yeh CT, Liang KH, Chang ML, Hsu CW, Chen YC, Lin CL, Lin WR, Lai MW. Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008-2012. Emerg Infect Dis. 2017 May;23(5):820-821. doi: 10.3201/eid2305.161894.
83. Lin JW, Chang ML, Hsu CW, Chen YC, Liang KH, Huang YH, Lin CC, Yeh CT. Acute exacerbation of hepatitis C in hepatocellular carcinoma patients receiving chemotherapy. J Med Virol. 2017 Jan;89(1):153-160. doi: 10.1002/jmv.24595.
84. Lin YT, Chien KY, Wu CC, Chang WY, Chu LJ, Chen MC, Yeh CT, Yu JS. Super-SILAC mix coupled with SIM/AIMS assays for targeted verification of phosphopeptides discovered in a large-scale phosphoproteome analysis of hepatocellular carcinoma. J Proteomics. 2017 Mar 22;157:40-51. doi: 10.1016/j.jprot.2017.02.005.
85. Wu RC, Chao AS, Lee LY, Lin G, Chen SJ, Lu YJ, Huang HJ, Yen CF, Han CM, Lee YS, Wang TH, Chao A. Massively parallel sequencing and genome-wide copy number analysis revealed a clonal relationship in benign metastasizing leiomyoma. Oncotarget. 2017 Jul 18;8(29):47547-47554. doi: 10.18632/oncotarget.17708.
86. Jusakul A, Cutcutache I, Yong CH, Lim JQ, Huang MN, Padmanabhan N, Nellore V, Kongpetch S, Ng AWT, Ng LM, Choo SP, Myint SS, Thanan R, Nagarajan S, Lim WK, Ng CCY, Boot A, Liu M, Ong CK, Rajasegaran V, Lie S, Lim AST, Lim TH, Tan J, Loh JL, McPherson JR, Khuntikeo N, Bhudhisawasdi V, Yongvanit P, Wongkham S, Totoki Y, Nakamura H, Arai Y, Yamasaki S, Chow PK, Chung AYF, Ooi LLPJ, Lim KH, Dima S, Duda DG, Popescu I, Broet P, Hsieh SY, Yu MC, Scarpa A, Lai J, Luo DX, Carvalho AL, Vettore AL, Rhee H, Park YN, Alexandrov LB, Gordân R, Rozen SG, Shibata T, Pairojkul C, Teh BT, Tan P.Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma. Cancer Discov. 2017 Oct;7(10):1116-1135. doi: 10.1158/2159-8290.CD-17-0368.
87. Ng AWT, Poon SL, Huang MN, Lim JQ, Boot A, Yu W, Suzuki Y, Thangaraju S, Ng CCY, Tan P, Pang ST, Huang HY, Yu MC, Lee PH, Hsieh SY, Chang AY, Teh BT, Rozen SG. Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia. SciTransl Med. 2017 Oct 18;9(412). pii: eaan6446. doi: 10.1126/scitranslmed.aan6446.
88. Lee TJ, Fu CH, Wang CH, Huang CC, Huang CC, Chang PH, Chen YW, Wu CC, Wu CL, Kuo HP. Impact of chronic rhinosinusitis on severe asthma patients. PLoS One. 2017 Feb 15;12(2):e0171047. doi: 10.1371/journal.pone.0171047.
89. Liu YS, Lin HY, Lai SW, Huang CY, Huang BR, Chen PY, Wei KC, Lu DY. MiR-181b modulates EGFR-dependent VCAM-1 expression and monocyte adhesion in glioblastoma. Oncogene. 2017 Aug 31;36(35):5006-5022. doi: 10.1038/onc.2017.129.
90. Chang KP, Wang CI, Pickering CR, Huang Y, Tsai CN, Tsang NM, Kao HK, Cheng MH, Myers JN. Prevalence of promoter mutations in the TERT gene in oral cavity squamous cell carcinoma. Head Neck. 2017 Jun;39(6):1131-1137. doi: 10.1002/hed.24728.
91. Kao HK, Abdelrahman M, Huang Y, Tsai CH, Barrera MJ, Tsang NM, Couves AJ, Cheng MH, Chang KP. Multiple concomitant oral cavity cancers: Incidence, management, and outcomes. J SurgOncol. 2017 Jun;115(7):835-841. doi: 10.1002/jso.24600.
92. Kuo IC, Kao HK, Huang Y, Wang CI, Yi JS, Liang Y, Liao CT, Yen TC, Wu CC, Chang KP. Endoplasmic reticulum aminopeptidase 2 involvement in metastasis of oral cavity squamous cell carcinoma discovered by proteome profiling of primary cancer cells. Oncotarget. 2017 Jun 27;8(37):61698-61708. doi: 10.18632/oncotarget.18680.
93. Liang KH, Yeh TS, Wu RC, Yeh CN, Yeh CT. GALNT14 genotype is associated with perineural invasion, lymph node metastasis and overall survival in resected cholangiocarcinoma.OncolLett. 2017 Jun;13(6):4215-4223. doi: 10.3892/ol.2017.5991.
94. Chen MY, Pai PC, Jung SM, Chuang CC, Chang CN, Wei KC. Prognostic effects of O6-Methylguanine DNA methyltransferase promoter hypermethylation in high-grade glioma patients with carmustine wafer implants. Formos J Surg. 2017. 50(2):45.
95. Hsu JT, Chen TD, Chuang HC, Huang SC, Le PH, Chen TH, Lin CJ, Yeh TS. Vascular endothelial growth factor expression is an independent poor prognostic factor for human epidermal growth factor receptor 2 positive gastric cancer. J Surg Res. 2017 Feb;208:40-50. doi: 10.1016/j.jss.2016.09.004.
96. Hsu JT, Wang CW, Le PH, Wu RC, Chen TH, Chiang KC, Lin CJ, Yeh TS. Clinicopathological characteristics and outcomes in stage I–III mucinous gastric adenocarcinoma: a retrospective study at a single medical center. World J SurgOncol. 2016 Apr 26;14:123. doi: 10.1186/s12957-016-0886-5.
97. Wang TH, Yu CC, Lin YS, Chen TC, Yeh CT, Liang KH, Shieh TM, Chen CY, Hsueh C. Long noncoding RNA CPS1-IT1 suppresses the metastasis of hepatocellular carcinoma by regulating HIF-1α activity and inhibiting epithelial-mesenchymaltransition.Oncotarget. 2016 Jul 12;7(28):43588-43603. doi:10.18632/oncotarget.9635.
98. Huang YH, Tseng YH, Lin WR, Hung G, Chen TC, Wang TH, Lee WC, Yeh CT. HBV polymerase overexpression due to large core gene deletion enhances hepatoma cell growth by binding inhibition of microRNA-100. Oncotarget. 2016 Feb 23;7(8):9448-61. doi: 10.18632/oncotarget.7021.
99. Wang TH, Yeh CT, Ho JY, Ng KF, Chen TC. OncomiR miR-96 and miR-182 promote cell proliferation and invasion through targeting ephrinA5 in hepatocellular carcinoma. MolCarcinog. 2016 Apr;55(4):366-75. doi: 10.1002/mc.22286. Epub 2015 Feb 8.
100.Chao A, Lin CY, Chao AN, Tsai CL, Chen MY, Lee LY, Chang TC, Wang TH, Lai CH, Wang HS. Lysine-specific demethylase 1 (LSD1) destabilizes p62 and inhibits autophagy in gynecologic malignancies. Oncotarget. 2017 Aug 10;8(43):74434-74450. doi: 10.18632/oncotarget.20158.
101.Wang TH, Yeh CT, Ho JY, Ng KF, Chen TC. OncomiR miR-96 and miR-182 promote cell proliferation and invasion through targeting ephrinA5 in hepatocellular carcinoma. MolCarcinog. 2016 Apr;55(4):366-75. doi: 10.1002/mc.22286. Epub 2015 Feb 8.
102.Wang CJ, Chen TC, Lin JH, Huang PR, Tsa HJ. One-step preparation of hydrophilic carbon nanofiber containing magnetic Ni nanoparticles materials and their application in drug delivery. J. Colloid Interface Sci. 2015 Feb;440:179–188.
103.Dutta A, Huang CT, Chen TC, Lin CY, Chiu CH, Lin YC, Chang CS, He YC. IL-10 inhibits neuraminidase-activated TGF-b and facilitates Th1 phenotype during early phase of infection. Nat. Commun.2015 Mar;6:6374. doi: 10.1038/ncomms7374.
104.Huang CT , Dutta A, Chen TC, Lin CY, Lin YC, Chang CS, He YC. Th17 deviation under influence of Th1 response attenuates the inflammation in late phase of influenza virus infection. The J. Immunol. 2015 May ;194: 148.6.
105.Huang CT, Dutta A, Chen TC, Lin CY, Chiu CH, Lin YC, Chang CS, He YC. IL-10 inhibits neuraminidase activated-TGF-β and facilitates Th1 phenotype during early phase of infection. The J. Immunol. 2015 May ;194: 74.6.
106.Hsieh CY, Chang MY, Chen KH, Jenq CC, Li YJ, Chen TC, Yang CW, Chen YM. Concurrent Cytomegalovirus Colitis and Bacteroidesfragilis Peritonitis in a Peritoneal Dialysis Patient. Perit Dial Int. 2015 Sep-Oct;35(5):587-8. doi: 10.3747/pdi.2014.00078.
107.Chang SD, Lin YH, Liang CC, Chen TC. Effects of sacral nerve stimulation on postpartum urinary retention-related changes in rat bladder. Taiwan J Obstet Gynecol. 2015 Dec;54(6):671-7. doi: 10.1016/j.tjog.2015.10.001.
108.Huang SC, Chuang HC, Chen TD, Chi CL, Ng KF, Yeh TS, Chen TC. Alterations of the mTOR pathway in hepatic angiomyolipoma with emphasis on the epithelioid variant and loss of heterogeneity of TSC1/TSC2. Histopathology. 2015 Apr;66(5):695-705. doi: 10.1111/his.12551.
109.Huang SF, Kuo IM, Lee CW, Pan KT, Chen TC, Lin CJ, Hwang TL, Yu MC. Comparison study of gastrinomas between gastric and non-gastric origins. World J SurgOncol. 2015 Jun 16;13:202. doi: 10.1186/s12957-015-0614-6
110.Tai HC, Chuang IC, Chen TC, Li CF, Huang SC, Kao YC, Lin PC, Tsai JW, Lan J, Yu SC, Yen SL, Jung SM, Liao KC, Fang FM, Huang HY. NAB2-STAT6 fusion types account for clinicopathological variations in solitary fibrous tumors. Mod Pathol. 2015 Oct;28(10):1324-35. doi: 10.1038/modpathol.2015.90.
111.Lin JD, Hsueh C, Chao TC.Long-Term Follow-Up of the Therapeutic Outcomes for Papillary Thyroid Carcinoma With Distant Metastasis. Medicine (Baltimore). 2015 Jul;94(26):e1063. doi: 10.1097/MD.0000000000001063
112.Liao CT, Fan KH, Kang CJ, Lin CY, Chang JT, Tsang NM, Huang BS, Chao YK, Lee LY, Hsueh C, Wang HM, Liau CT, Hsu CL, Hsieh CH, Ng SH, Lin CH, Tsao CK, Fang TJ, Huang SF, Chang KP, Yen TC. Clinical Outcomes of Patients with Resected Oral Cavity Cancer and Simultaneous Second Primary Malignancies. PLoS One. 2015 Sep 3;10(9):e0136918. doi: 10.1371/journal.pone.0136918.
113.Liu FH, Kuo SF, Hsueh C, Chao TC, Lin JD. Postoperative recurrence of papillary thyroid carcinoma with lymph node metastasis. J SurgOncol. 2015 Aug;112(2):149-54. doi: 10.1002/jso.23967.
114.Chuang WY, Chang H, Shih LY, Wang PN, Chang YS, Lin TL, Hung YS, Yeh CJ, Ueng SH, Tang TC, Kuo MC, Dunn P, Wu JH, Kao HW, Ou CW, Wan YL, Hsueh C. CD5 positivity is an independent adverse prognostic factor in elderly patients with diffuse large B cell lymphoma. Virchows Arch. 2015 Nov;467(5):571-82. doi: 10.1007/s00428-015-1845-1.
115.Chuang WY, Chang YS, Chao YK, Yeh CJ, Liu YH, Tseng CK, Chang HK, Wan YL, Hsueh C. High sex determining region Y-box 2 (SOX2) expression correlates with absence of nodal metastasis in esophageal squamous cell carcinoma. Int J ClinExpPathol. 2015 Aug 1;8(8):9248-55.
116.Lee CW, Chang KP, Chen YY, Liang Y, Hsueh C, Yu JS, Chang YS, Yu CJ. Overexpressed tryptophanyl-tRNAsynthetase, an angiostatic protein, enhances oral cancer cell invasiveness. Oncotarget. 2015 Sep 8;6(26):21979-92.
117.Lai CY, Chao TC, Lin JD, Hsueh C. Sclerosingmucoepidermoid carcinoma with eosinophilia of thyroid gland in a male patient: a case report and literature review. Int J ClinExpPathol. 2015 May 1;8(5):5947-51. eCollection 2015.
118.Yang W, Lai JY, Chao HC, Hsueh C. Gallbladder teratoma and a review of the literature. PediatrNeonatol. 2015 Apr;56(2):134-5. doi: 10.1016/j.pedneo.2014.06.008.
119.Lee LA, Huang CG, Tsao KC, Liao CT, Kang CJ, Chang KP, Huang SF, Chen IH, Fang TJ, Li HY, Yang SL, Lee LY, Hsueh C, Lin CY, Fan KH, Chang TC, Wang HM, Ng SH, Yen TC.Human Papillomavirus Infections are Common and Predict Mortality in a Retrospective Cohort Study of Taiwanese Patients With Oral Cavity Cancer. Medicine (Baltimore). 2015 Nov;94(47):e2069. doi: 10.1097/MD.0000000000002069.
120.Chuang WY, Chang YS, Chao YK, Yeh CJ, Ueng SH, Chang CY, Liu YH, Tseng CK, Chang HK, Wan YL, Hsueh C. Phosphorylated mTOR expression correlates with podoplanin expression and high tumor grade in esophageal squamous cell carcinoma. Int J ClinExpPathol. 2015 Oct 1;8(10):12757-65. eCollection 2015.
121.Hsia SM, Yu CC, Shih YH, Yuanchien Chen M, Wang TH, Huang YT, Shieh TM.Isoliquiritigenin as a cause of DNA damage and inhibitor of ataxia-telangiectasia mutated expression leading to G2/M phase arrest and apoptosis in oral squamous cell carcinoma. Head Neck. 2015 Jan 10. doi: 10.1002/hed.24001.
122.Yeh CT, Ho JY, Ng KF, Chen TC. OncomiR miR-96 and miR-182 promote cell proliferation and invasion through targeting ephrinA5 in hepatocellular carcinoma. Wang TH, MolCarcinog. 2015 Feb 8. doi: 10.1002/mc.22286.
123.Shih, Y. H., Chang, K. W., Yu, C. C., Kao, M. C., Chen, M. Y., Wang, T. H.,Shieh, T. M. Hinokitiol suppressed pan-histone expression and cell growth in oral squamous cell carcinoma cells. J. Funct. Food. 2015. 15:452-463.
124.Hu FW, Lee SS, Yang LC, Tsai CH, Wang TH, Chou MY, Yu CC. Knockdown of S100A4 impairs arecoline-induced invasiveness of oral squamous cell carcinomas. Oral Oncol. 2015 Jul;51(7):690-7. doi: 10.1016/j.oraloncology.2015.04.003. Epub 2015 Apr 23.
125.Wang TH, Lin YS, Chen Y, Yeh CT, Huang YL, Hsieh TH, Shieh TM, Hsueh C, Chen TC. Long non-coding RNA AOC4P suppresses hepatocellular carcinoma metastasis by enhancing vimentin degradation and inhibiting epithelial-mesenchymal transition. Oncotarget. 2015 Sep 15;6(27):23342-57.
126.Wang TH, Chen TC, Teng X, Liang KH, Yeh CT. Automated biphasic morphological assessment of hepatitis B-related liver fibrosis using second harmonic generation microscopy. Sci Rep. 2015 Aug 11;5:12962. doi: 10.1038/srep12962.
127.Wang CJ, Chen TC, Lin JH, Huang PR, Tsai HJ, Chen CS. One-step preparation of hydrophilic carbon nanofiber containing magnetic Ni nanoparticles materials and their application in drug delivery. J Colloid Interface Sci. 2015 Feb 15;440:179-88. doi: 10.1016/j.jcis.2014.10.073. Epub 2014 Nov 8.
128.Huang SC, Chuang HC, Chen TD, Chi CL, Ng KF, Yeh TS, Chen TC. Alterations of the mTOR pathway in hepatic angiomyolipoma with emphasis on the epithelioid variant and loss of heterogeneity of TSC1/TSC2. Histopathology 2015 DOI: 10.1111/his.12551
129.Hsieh CY, Chang MY, Chen KH, Jenq CC, Li YJ, Chen TC, Yang CW, Chen YM. Concurrent Cytomegalovirus Colitis and Bacteroidesfragilis Peritonitis in a Peritoneal Dialysis Patient. Perit Dial Int. 2015 Sep-Oct;35(5):587-8. doi: 10.3747/pdi.2014.00078.
130.Yang W, Lai JY, Chao HC, Hsueh C. Gallbladder teratoma and a review of the literature. PediatrNeonatol. 2015 Apr;56(2):134-5. doi: 10.1016/j.pedneo.2014.06.008.
131.Huang SC, Ng KF, Lee SE, Chen KH, Yeh TS, Chen TC. HER2 testing in paired biopsy and excision specimens of gastric cancer: the reliability of the scoring system and the clinicopathological factors relevant to discordance. Gastric Cancer. 2014 Dec 17. DOI 10.1007/s10120-014-0453-0
132.Wang CJ, Chen TC, Lin JH, Huang PR, Tsai HJ, Chen CS. One-step preparation of hydrophilic carbon nanofiber containing magnetic Ni nanoparticles materials and their application in drug delivery. J Colloid Interface Sci. 2015 Feb 15;440:179-88. doi: 10.1016/j.jcis.2014.10.073. Epub 2014 Nov 8.
133.Hung TH, Hsu SC, Cheng CY, Choo KB, Tseng CP, Chen TC, Lan YW, Huang TT, Lai HC, Chen CM, Chong KY. Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/β-catenin pathway. Oncotarget. 2014 Dec 15;5(23):12273-90.
134.Cheng CT, Tsai CY, Yeh CN, Chiang KC, Chen YY, Wang SY, Chen TW, Tseng JH, Jung SM, Chen TC, Yeh TS. Clinical significance of pathological complete response in patients with metastatic gastrointestinal stromal tumors after imatinibmesylate treatment--lessons learned. Anticancer Res. 2014 Nov;34(11):6617-25.
135.Hsiao CC, Wang WC, Kuo WL, Chen HY, Chen TC, Hamann J, Lin HH. CD97 inhibits cell migration in human fibrosarcoma cells by modulating TIMP-2/MT1- MMP/MMP-2 activity--role of GPS autoproteolysis and functional cooperation between the N- and C-terminal fragments. FEBS J. 2014 Nov;281(21):4878-91. doi: 10.1111/febs.13027. Epub 2014 Sep 22.
136.Huang CG, Lee LA, Tsao KC, Liao CT, Yang LY, Kang CJ, Chang KP, Huang SF, Chen IH, Yang SL, Lee LY, Hsueh C, Chen TC, Lin CY, Fan KH, Chang TC, Wang HM, Ng SH, Yen TC. Human papillomavirus 16/18 E7 viral loads predict distant metastasis in oral cavity squamous cell carcinoma. J ClinVirol. 2014 Oct;61(2):230-6. doi: 10.1016/j.jcv.2014.07.007. Epub 2014 Jul 22.
137.Huang SC, Ng KF, Chen KH, Hsu JT, Liu KH, Yeh TS, Chen TC. Prognostic factors in Epstein-Barr virus-associated stage I-III gastric carcinoma: implications for a unique type of carcinogenesis. Oncol Rep. 2014 Aug;32(2):530-8. doi: 10.3892/or.2014.3234. Epub 2014 Jun 5.
138.LE PH, Huang SC, Lim SN, Chou CH, Yeh TS, Chen TC, Yen TH, Su MY, Chiu CT, Yeh CT, Lin WR. Complex IV subunit 1 defect predicts postoperative survival in hepatocellular carcinoma. OncolLett. 2014 May;7(5):1430-1438. Epub 2014 Mar 11.
139.Chen HH, Lin MW, Tien WT, Lai CP, Weng KY, Ko CH, Lin CC, Chen JC, Tiao KT, Chen TC, Chen SC, Yeh TS, Cheng CF. High-purity separation of cancer cells by optically induced dielectrophoresis. J Biomed Opt. 2014 Apr;19(4):045002. doi: 10.1117/1.JBO.19.4.045002.
140.Chen KH, Hsu SC, Chen HY, Ng KF, Chen TC. Utility of fluorescence in situ hybridization for ploidy and p57 immunostaining in discriminating hydatidiform moles. BiochemBiophys Res Commun. 2014 Apr 4;446(2):555-60. doi: 10.1016/j.bbrc.2014.03.003. Epub 2014 Mar 12.
141.Hung YS, Chou WC, Chen TD, Chen TC, Wang PN, Chang H, Hsu HC, Shen WC, Cheng WH, Chen JS. Prognostic factors in adult patients with solid cancers and bone marrow metastases. Asian Pac J Cancer Prev. 2014;15(1):61-7.
142.Liang CC, Lin YH, Chen TC, Chang SD. How antepartum and postpartum acute urinary retention affects the function and structure of the rat bladder. IntUrogynecol J. 2014 Aug;25(8):1105-13. doi: 10.1007/s00192-013-2320-7. Epub 2014 Feb 11.
143.Yeh CT, Huang YH, Liang KH, Chang ML, Hsu CW, Chen YC, Chen TC, Yeh TS, Lee WC. Segregation of signaling proteins as prognostic predictors for local recurrence and distant metastasis in hepatocellular carcinoma. Int J Oncol. 2014 Feb;44(2):491-504. doi: 10.3892/ijo.2013.2198. Epub 2013 Nov 29.
144.Yeh TS1, Wang F, Chen TC, Yeh CN, Yu MC, Jan YY, Chen MF. Expression profile of microRNA-200 family in hepatocellular carcinoma with bile duct tumor thrombus. Ann Surg. 2014 Feb;259(2):346-54. doi: 10.1097/SLA.0000000000000223.
145.Chou WC, Chen JS, Hung YS, Hsu JT, Chen TC, Sun CF, Lu CH, Hwang TL. Plasma chromogranin A levels predict survival and tumor response in patients with advanced gastroenteropancreatic neuroendocrine tumors. Anticancer Res. 2014 Oct;34(10):5661-9.
146.Yeh CT, Huang YH, Liang KH, Chang ML, Hsu CW, Chen YC, Chen TC, Yeh TS, Lee WC. Segregation of signaling proteins as prognostic predictors for local recurrence and distant metastasis in hepatocellular carcinoma. Int J Oncol. 2014 Feb;44(2):491-504. doi: 10.3892/ijo.2013.2198. Epub 2013 Nov 29.
147.Dutta A, Miaw SC, Yu JS, Chen TC, Lin CY, Lin YC, Chang CS, He YC, Chuang SH, Yen MI, Huang CT. Altered T-bet dominance in IFN-g-decoupled CD4+ T Cells with attenuated cytokine storm and preserved memory in influenza. The Journal of Immunology 2013, 190:4205-4214. April.
148.Yeh CT, Liang KH, Chang ML, Hsu CW, Chen YC, Lin CL, Lin WR, Lai MW. Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008-2012. Emerg Infect Dis. 2017 May;23(5):820-821. doi: 10.3201/eid2305.161894.
149.Chen TC, Jan YY, Yeh TS. K-ras mutation is strongly associated with perineural invasion and represents an independent prognostic factor of intrahepatic cholangiocarcinoma after hepatectomy. Ann SurgOncol 2012 Jul;19Suppl 3:S675-81.
150.Chao A, Chen TC, Hsueh C, Huang CC, Yang JE, Hsueh S, Huang HJ, Lin CT, Tang YH, Liou JD, Chang CJ, Chou HH, Lai CH. Human Papillomavirus in vaginal intraepithelial neoplasia. Int J cancer Int J Cancer. 2012 Aug 1; 131(3):E259-68. (Co-first author)
151.Wang TH, Chang JL, HO JY, Wu HC, Chen TC＊. EphrinA5 suppresses colon cancer development by negatively regulating EGFR stability. FEBS j 2012; 279(2):251-63. (Corresponding author).
152.Chang LY, Lin YC, Mahalingam J, Huang CT, Chen TW, Kang CW, Peng HM, Chu YY, Chiang JM, Dutta A, Day YJ, Chen TC, Yeh CT, Lin CY. Tumor-derived chemokine CCL5 enhances TGF-ss mediated killing of CD8+ T cells in colon cancer by T regulatory cells. Cancer Res. 2012 Mar 1;72(5):1092-102.
153.Wu TH, Yu MC, Chen TC, Lee CF, Chan KM, Wu TJ, Chou HS, Lee WC, Chen MF. Encapsulation is a significant prognostic factor for better outcome in large hepatocellular carcinoma. J SurgOncol. 2012 Jan;105(1):85-90.
154.Huang SC, Chang HC, Yeh TS, Ng KF, Chen TC. Hepatoidmicrocarcinoma of the pancreas: A case report and review of the literature. Chang Gung Medical Journal 2012; 35:285-91. (Corresponding author).
155.Chou WC, Hung YS, Hsu JT, Chen JS, Lu CH, Hwang TL, Rau KM, Yeh KY, Chen TC, Sun CF. Chromogranin A Is a Reliable Biomarker for Gastroenteropancreatic Neuroendocrine Tumors in an Asian Population of Patients. Neuroendocrinology. 2012 Feb 14
156.Wu TJ, Chen TC, Wang F, Chan KM, Soong RS, Chou HS, Lee WC, Yeh CT. Large fragment pre-s deletion and high viral load independently predict hepatitis B relapse after liver transplantation.PLoS One. 2012;7(2):e32189. Epub 2012 Feb 21
157.Chang JWC, Wei NC, Su HJ, Huang JL, Chen TC, Wu YC, Yu CT, Hou MM, Hsieh CH, Hsieh JJ, Wu CE, Cheng HY, Hsu T, Wang TH. Comparison of genomic signatures of non-small cell lung cancer recurrence between two microarray platforms. Anticancer Res 2012; 32(4): 1259-65.
158.Huang YH, Lin KH, Chen HC, Chang ML, Hsu CW, Lai MW, Chen TC, Lee WC, Tseng YH, Yeh CT. Identification of Postoperative Prognostic MicroRNA Predictors in Hepatocellular Carcinoma. PLoS One 2012; 7(5):e37188.
159.Chang LY, Lin YC, Kang CW, Hsu CY, Chu YY, Huang CT, Day YJ, Chen TC, Yeh CT, Lin CY. The Indispensable Role of CCR5 for In Vivo Suppressor Function of Tumor-Derived CD103+ Effector/Memory Regulatory T Cells. J Immunol 2012 Jul 15; 189(2):567-74.
160.Chen CS, Chen TC, Chen CC, Lai YT, You JH, Chou TM, Chen CH, Lee JF. Effect of Ti3+ on TiO2-supported Cu catalysis used for CO oxidation. Langmuir 2012 Jul 3; 28(26): 9996-10006.
161.Lee LA, Huang CG, Liao CT, Lee LY, Hsueh C, Chen TC, Lin CY, Fan KH, Wang HM, Huang SF, Chen IH, Kang CJ, Ng SH, Yang SL, Tsao KC, Chang YL, Yen TC. Human papillomavirus-16 infection in advanced oral cavity cancer patients is related to an increased risk of distant metastases and poor survival. PLoS One. 2012; 7(7): e40767.
162.Wang TH, Ng KF, Yeh TS, Wang YL, Liang KH, Yeh CT, Chen TC*. Peritumoral small ephrinA5 isoform level predicts the postoperative survival in hepatocellular carcinoma. PLoS One. 2012; 7(7): e41749. (Corresponding author)
163.Yeh CN, Yeh TS, Chen TC, Jan YY, Chen MF. Gross pathological classification of peripheral cholangiocarcinoma determines the efficacy of hepatectomy.JGastroenterol. 2012 Sep 25.
164.Lai CH, Chou HH, Chang CJ, Wang CC, Hsueh S, Huang YT, Chen YR, Chang HP, Chang SC, Lin CT, Chao A, Qiu JT, Huang KG, Chen TC, Jao MS, Chen MY, Liou JD, Huang CC, Chang TC, Patsner B. Clinical implications of human papillomavirus genotype in cervical adeno-adenosquamous carcinoma. Euro J Cancer Eur J Cancer. 2012 Sep 29
165.Lo SJ, Fan LC, Tsai YF, Lin KY, Huang HL, Wang TH, Liu H, Chen TC, Huang SF, Chang CJ, Lin YJ, Yung BY, Hsieh SY. A novel interaction of nucleophosmin with BCL2-Associated X protein regulating death evasion and drug sensitivity in human hepatoma cells. Hepatology. 2012 Dec 19. doi: 10.1002/hep.26209.
166.Yeh TS, Chen TC, Yeh CN, et al. Expression profile of microRNA-200 family in hepatocellular carcinoma with bile duct tumor thrombus. Ann Surg 2012 (in press) IF=7.492 R/C=1/199)
167.Chang YT, Wu CC, Shyr YM, Chen TC, Hwang TL, Yeh TS, Chang KP, Liu HP, Liu YL, Tsai MH, Chang YS, Yu JS. Secretome-Based Identification of ULBP2 as a Novel Serum Marker for Pancreatic Cancer Detection. PLoS One. 2011;6(5):e20029. Epub 2011 May 20.
168.Tsai CY, Lin YS, Yeh TS, Cheong CF, Chang CH, Chen TC, Chen MF. Disrupted hepatic adiponectin signaling impairs liver regeneration of steatotic rats. Chang Gung Med J. 2011 May-Jun;34(3):248-59.
169.Chang KW, Chou A, Lee CC, Yeh C, Lai MW, Yeh TS, Chen TC, Liang KH, Yeh CT. Overexpression of {kappa}-Actin Alters Growth Properties of Hepatoma Cells and Predicts Poor Postoperative Prognosis. Anticancer Res. 2011 Jun;31(6):2037-44.
170.Wu TH, Yu MC, Chan KM, Lee CF, Chen TC, Chang HC, Chou HS, Wu TJ, Eldeen FZ, Chen MF, Lee WC. Prognostic effect of steatosis on hepatocellular carcinoma patients after liver resection. Eur J SurgOncol. 2011 Jun 1.
171.Chou CC, Chang PC, Wen MS, Lee, HL, Chen TC, Yeh SJ, Wu D. Epicardial ablation of rotors supressesinducibility of acetylcholine-induced atrial fibrillation in left pulmonary vein-left atrium preparations in a beagle heart failure model. J Am CollCardiol. 2011 Jul 5;58(2):158-66.
172.Sung KF, Chu YY, Liu NJ, Hung CF, Chen TC, Chen JS, Lin CH. Direct peroralcholangioscopy and pancreatoscopy for diagnosis of a pancreatobiliary fistula caused by an intraductal papillary mucinous neoplasm of the pancreas: a case report. Dig Endosc. 2011 Jul;23(3):247-50.
173.Yu MC, Lee YS, Lin SE, Wu HY, Chen TC, Lee WC, Chen MF, Tsai CN. Recurrence and Poor Prognosis Following Resection of Small Hepatitis B-Related Hepatocellular Carcinoma Lesions Are Associated with Aberrant Tumor Expression Profiles of Glypican 3 and Osteopontin. Ann SurgOncol. 2011 Aug 6.
174.Peng CH, Liao CT, Peng SC, Chen YJ, Cheng AJ, Juang JL, Tsai CY, Chen TC, Chuang YJ, Tang CY, Hsieh WP, Yen TC. A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma. PLoS One. 2011;6(8):e23452. Epub 2011 Aug 11
175.Hsieh SY, He JR, Yu MC, Lee WC, Chen TC, Lo SJ, Bera R, Sung CM, Chiu CT. Secreted ERBB3 Isoforms are Serum Markers for Early Hepatoma in Patients with Chronic Hepatitis and Cirrhosis. J Proteome Res. 2011 Oct 7;10(10):4715-24.
176.Hsu JT, Chen TC, Tseng JH, Chiu CT, Liu KH, Yeh CN, Hwang TL, Jan YY, Yeh TS. Impact of HER-2 overexpression/amplification on the prognosis of gastric cancer patients undergoing resection: A single-center study of 1,036 patients. Oncologist 2011, 16(12): 1706-13. (Co-first author)
177.Yeh CT, Chen T, Hsu CW, Chen YC, Lai MW, Liang KH, Chen TC. Emergence of the rtA181T/sW172* mutant increased the risk of hepatoma occurrence in patients with lamivudine-resistant chronic hepatitis B. BMC Cancer. 2011 Sep 21;11(1):398.
178.Cheng CH, Lee CF, Wu TH, Chan KM, Chou HS, Wu TJ, Yu MC, Chen TC, Lee WC, Chen MF. Evaluation of the new AJCC staging system for resectable hepatocellular carcinoma. World J SurgOncol. 2011 Sep 30;9(1):114.
179.Chao A, Jao MS, Huang CC, Huang HJ, Cheng HH, Yang JE, Hsueh S, Chen TC, QiuJT,Lin CT, Fu CJ, Chou HH,>Lai CH. Human papillomavirus genotype in cervical intraepithelial neoplasia grade 2 and 3 of Taiwanese women. Int J Cancer. 2011 Feb 1;128(3):653-9.
180.Kuo WL, Yu MC, Lee JF, Tsai CN, Chen TC, Chen MF. ImatinibMesylate Improves Liver Regeneration and Attenuates Liver Fibrogenesis in CCL(4)-Treated Mice. J Gastrointest Surg. 2011 Nov 9. Hsu SC, Huang CK, Chen TC*. The importance of HER2 testing quality. BioMedicine 2011; Nov 4(4): 207-19. (Corresponding author)
181.Hsu SC, Huang CK, Chen TC*. Clinical Audit of HER2 Testing. BioMedicine 2011; Nov 4(4): 220-3. (Corresponding author)
182.Chang HC, Huang SC, Chen TC, Law MW, Chen SY, Lai JY. Y-shaped colonic duplication: report of a case and literature review. Chang Gung Med J 2011; 34(6 Suppl): 43-7.