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李志宏 醫師

皮膚免疫學、皮膚生理學、乾癬、異位性皮膚炎

教職 : 教授

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語言

  • 國語,英語,閩南語

現職

  • 高雄長庚紀念醫院皮膚部教授級主治醫師
  • 長庚大學醫學院兼任教授
  • 臺灣教育部部定教授
  • 臺灣皮膚科醫學會常務理事
  • 臺灣研究皮膚科學會秘書長
  • Dermatologica Sinica主編(SCI雜誌)

學歷

  • 高雄醫學大學醫學博士
  • 高雄醫學院醫學士

經歷

  • 高雄長庚紀念醫院皮膚部主任(2013~2020)
  • Dermatologica Sinica主編(SCI雜誌)(2018~)
  • 台灣皮膚科醫學會常務理事(2018~)
  • 台灣皮膚科醫學會理事(2015~)
  • 台灣研究皮膚科學會秘書長(2018~)
  • 台灣研究皮膚科學會常務理事(2012~2018)
  • 高雄醫學大學皮膚科部定副教授(2012-2013)
  • 高雄醫學大學皮膚科部定助理教授(2009-2012)
  • 高雄市立小港醫院皮膚科主任(2008-2013)
  • 美國NIH國家癌症中心客座學者(2004-2006)
  • 高雄醫學大學附設醫院主治醫師(2003-2013)

學會與認證

  • 台灣皮膚科醫學會專科醫師
  • 台灣皮膚科醫學會常務理事
  • 台灣研究皮膚科學會秘書長
  • 台灣乾癬免疫學會理事
  • 台灣教育部部定教授
  • 台灣醫學教育學會會員
  • 美國研究皮膚科學會會員

論文及期刊發表

  • CCL21 Induces mTOR-dependent MALAT1 expression, leading to cell migration in cutaneous T-cell lymphoma.
  • Identification of pyruvatekinase 2 as a possible crab allergen and analysis of allergenic proteins in crabs consumed in Taiwan.
  • MiR-146a-5p expression in peripheral CD14?monocytes from patients with psoriatic arthritis induces osteoclast activation, bone resorption, and correlates with clinical response. �
  • Treatment with TNF-a inhibitor rectified M1 macrophage polarization from blood CD14+ monocytes in patients with psoriasis independent of STAT1 and IRF-1 activation.
  • Early sign of microangiopathy in systemic sclerosis: the significance of cold stress test in dynamic laser Doppler flowmeter.
  • Identification of pyruvate kinase as a novel allergen in whiteleg shrimp (Litopenaeus vannamei) by specific-IgE present in patients with shrimp allergy.
  • Clinicopathological features and course of cutaneous protothecosis.
  • Pathophysiology of arsenic-induced adverse health effects.
  • Solanum incanum extract (SR-T100) induces melanoma cell apoptosis and inhibits established lung metastasis.
  • Inflammatory and noninflammatory itch: implications in pathophysiology-directed treatments.
  • Chronic eczematous dermatitis in patients with neurodegenerative diseases may be an early marker of bullous pemphigoid.
  • Linear and whorled nevoid hypermelanosis versus incontinentia pigmenti: Pigmentary incontinence is not a differential histological feature.
  • Differential activation behavior of dermal dendritic cells underlies the strain-specific Th1 responses to single epicutaneous immunization.
  • Treatment of pigmented basal cell carcinoma with 3?mm surgical margin in Asians. �
  • Presence of the Merkel cell polyomavirus in Merkel cell carcinoma combined with squamous cell carcinoma in a patient with chronic arsenism.
  • Role of mitochondria, ROS, and DNA damage in arsenic induced carcinogenesis.
  • Benzopyrene, a major polyaromatic hydrocarbon in smoke fume, mobilizes Langerhans cells and polarizes Th2/17 responses in epicutaneous protein sensitization through the aryl hydrocarbon receptor.
  • Progression of idiopathic eruptive macular pigmentation in a girl from childhood to adolescence.
  • Cumulative arsenic exposure is associated with fungal infections: two cohort studies based on southwestern and northeastern basins in Taiwan.
  • Arsenite regulates prolongation of glycan residues of membrane glycoprotein: a pivotal study via wax physisorption kinetics and FTIR imaging.
  • Differential immunological effects of infrared irradiation and its associated heat in vivo.
  • An estimation of the incidence of tuberous sclerosis complex by a nationwide retrospective cohort study from 1997 to 2010.
  • Bull's eye dermatoscopy pattern at Bacillus Calmettee-Guerin inoculation site correlates with systemic involvements in patients with Kawasaki disease.
  • Web-based learning system for developing and assessing clinical diagnostic skills for dermatology residency program.
  • Effect of heme oxygenase-1 gene promoter polymorphism on cancer risk by histological subtype: A prospective study in arseniasis-endemic areas in Taiwan.
  • Immune regulation in pathophysiology and targeted therapy for itch in atopic dermatitis.
  • Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature.
  • No Significant Reduction of Circulating Endothelial-Derived and Platelet-Derived Microparticles in Patients with Psoriasis Successfully Treated with Anti-IL12/23
  • Dermal dendritic cells, but not Langerhans cells, are critical in murine single epicutaneous sensitization.
  • IL-9 induces IL-8 production via STIM1 activation and ERK phosphorylation in epidermal keratinocytes: A plausible mechanism of IL-9R in atopic dermatitis.
  • STAT3-dependent VEGF production from keratinocytes abrogates dendritic cell activation and migration by arsenic: a plausible regional mechanism of immunosuppression in arsenical cancers.
  • Prurigo Nodularis Is Associated with Depression and Anxiety in Chronic Hemodialysis Patients
  • Taiwanese Dermatological Association consensus for the management of atopic dermatitis.
  • Association between the synthetic vascular stent used for abdominal aortic aneurysm and generalized granuloma annulare.
  • Refractory urticaria in adult-onset Still's disease.
  • Betel chewing and arecoline affects eotaxin-1, asthma and lung function.
  • Female gender and acne disease are jointly and independently associated with the risk of major depression and suicide: A national population-based study
  • Primary cutaneous tuberculosis in an elderly man.
  • A polymorphism of ORAI1 rs7135617, is associated with susceptibility to rheumatoid arthritis.
  • Apoptosis Induced by 2-Aryl Benzothiazoles-Mediated Photodynamic Therapy in Melanomas via Mitochondrial Dysfunction.
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