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李劭軒

高雄長庚醫院 血液腫瘤科主治醫師

血液腫瘤科

乳癌、肺癌、大腸直腸癌、食道癌、頭頸部腫瘤

教職 : 教授

醫師網路掛號

※直接點選進入醫師網路掛號畫面※

語言

  • 國語,英語,閩南語

現職

  • 高雄長庚醫院 血液腫瘤科主治醫師

學歷

  • 高雄醫學大學醫學系畢業

經歷

  • 高雄長庚醫院 內科部住院醫師
  • 高雄長庚醫院 血液腫瘤科住院醫師

學會與認證

  • 台灣內科醫學會
  • 中華民國癌症醫學會

論文及期刊發表

  • High expression of endoglin in primary breast cancer may predict response to neoadjuvant chemotherapy. Mol Med Rep. 2017 Nov;16(5):7185-7190. (SCI; IF=1.692; Medicine, research & experimental=85/128)
  • Develop and validation a nomogram to predict the recurrent probability in patients with major salivary gland cancer. J Cancer. 2017 Jul 20;8(12):2247-2255. (SCI; IF=2.916,Oncology 113/217)
  • Treatment Outcomes of Patients with Locally Advanced Synchronous Esophageal and Head/Neck Squamous Cell Carcinoma Receiving Curative Concurrent Chemoradiotherapy. International Journal of Head and Neck Science 1(2): 121-130, 2017. (non SCI; corresponding author*)
  • Prognosis of neutrophil-to-lymphocyte ratio in clinical early-stage tongue (cT1/T2N0) cancer. Onco Targets Ther. 2017; 10: 3917–3924. (SCI; IF=2.612; Biotechnology & applied microbiology 61/160)
  • Mitochondrial assembly receptor expression is an independent prognosticator for patients with oral tongue squamous cell carcinoma. J Renin Angiotensin Aldosterone Syst. 2017 Jul-Sep;18(3):1470320317717904. (SCI; IF=1.396; Peripheral vascular disease 51/63; corresponding author*)
  • A novel therapeutic approach for esophageal squamous cell carcinoma: suppressor of cytokine signaling-1 gene therapy. J Thorac Dis. 2017 Jun; 9(6): 1446–1449. (SCI; IF=2.365; Respiratory system 36/59; corresponding author*)
  • The impact of de novo liver metastasis on clinical outcome in patients with advanced non-small-cell lung cancer. PLoS One. 2017 Jun 7;12(6):e0178676 (SCI; IF=2.806; Multidisciplinary sciences 15/64).
  • Screening for Psychologic Distress in Taiwanese Cancer Inpatients Using the National Comprehensive Cancer Network Distress Thermometer: The Effects of Patients’ Sex and Chemotherapy Experience. Psychosomatics. 2017 Apr 6. pii: S0033-3182(17)30093-2. (SCI; IF=1.436; PSYCHOLOGY 52/77)
  • Plasma DNA Mediate Autonomic Dysfunctions and White Matter Injuries in Patients with Parkinson` Disease. Oxid Med Cell Longev. 2017;2017:7371403. doi: 10.1155/2017/7371403. Epub 2017 Jan 23. (SCI; IF=4.593, Cell biology 56/180)
  • Areca nut is associated with younger age of diagnosis, poor chemoradiotherapy response, and shorter overall survival in esophageal squamous cell carcinoma. PLoS One. 2017 Feb 28;12(2):e0172752 (SCI; IF=2.806; Multidisciplinary sciences 15/64; corresponding author*)
  • Buparlisib and paclitaxel in patients with platinum-pretreated recurrent or metastatic squamous cell carcinoma of the head and neck (BERIL-1): a randomised, double-blind, placebo-controlled phase 2 trial. Lancet Oncol. 2017 Mar;18(3):323-335. (SCI; IF=33.9; Oncology 3/217)
  • Treatment Outcomes of Patients with Locally Advanced Synchronous Esophageal and Head/Neck Squamous Cell Carcinoma Receiving Curative Concurrent Chemoradiotherapy. Scientific Reports. 2017 Jan 30;7:41785 (SCI; IF=4.259; Multidisciplinary sciences 10/64; corresponding author*)
  • FDG PET using SUVmax for preoperative T-staging of esophageal squamous cell carcinoma with and without neoadjuvant chemoradiotherapy. BMC Med Imaging. 2017 Jan 5;17(1):1 (SCI; IF=1.060; Radiology, Nuclear medicine & Medical imaging 104/127; corresponding author*)
  • Prevalence and related factors of psychological distress among cancer inpatients using routine Distress Thermometer and Chinese Health Questionnaire screening. Neuropsychiatr Dis Treat. 2016 Oct 25;12:2765-2773 (SCI; IF=2.198; PSYCHIATRY 76/142)
  • Validation and Comparison of the 7th Edition of the American Joint Committee on Cancer Staging System and Other Prognostic Models to Predict Relapse-Free Survival in Asian Patients with Parotid Cancer. J Cancer. 2016 Aug 15;7(13):1833-1841. eCollection 2016. (SCI; IF=2.916, Oncology 113/217)
  • Altered Striatocerebellar Metabolism and Systemic Inflammation in Parkinson` Disease. Oxid Med Cell Longev. 2016;2016:1810289. Epub 2016 Sep 1. (SCI; IF=4.593, Cell biology 56/190)
  • The Therapeutic Benefit of Radical Resection for T4b Oral Cavity Squamous Cell Carcinoma with Partial or Complete Response After Radical Chemo-Intensity-Modulated Radiotherapy (IMRT). Ann Surg Oncol. 2016 Sep 9. [Epub ahead of print] (SCI, IF=4.041; Surgery 17/196)
  • Angiotensin II type I receptor (AT1R) is an independent prognosticator of esophageal squamous cell carcinoma and promotes cells proliferation via mTOR activation. Oncotarget. 2016 Oct 11;7(41):67150-67165 (SCI; IF=5.168, Oncology 44/217; first author)
  • Transcriptomic reappraisal identifies MGLL overexpression as an unfavorable prognosticator in primary gastrointestinal stromal tumors.Oncotarget. 2016 Jun 27. doi: 10.18632/oncotarget.10304. [Epub ahead of print] (SCI; IF=5.168, Oncology 44/217)
  • Betel nut chewing history is an independent prognosticator for smoking patients with locally advanced stage IV head and neck squamous cell carcinoma receiving induction chemotherapy with docetaxel, cisplatin, and fluorouracil. World J Surg Oncol. 2016 Mar 22;14:86. doi: 10.1186/s12957-016-0844-2. (SCI; IF=1.600; Surgery 107/196; corresponding author*)
  • Significance of mammalian target of rapamycin in patients with locally advanced stage IV head and neck squamous cell carcinoma receiving induction chemotherapy with docetaxel, cisplatin, and fluorouracil. Head Neck. 2016 Apr;38 Suppl 1:E844-52. doi: 10.1002/hed.24111. (SCI; IF=3.376; Otorhinolaryngology 1/42; first author)
  • Development and Validation of a Prognostic Score to Predict Survival in Adult Patients With Solid Tumors and Bone Marrow Metastases. Medicine (Baltimore). 2015 Jun;94(23):e966. (SCI; IF=1.804; MEDICINE, GENERAL & INTERNAL 57/155)
  • Brain mediators of systemic oxidative stress on perceptual impairments in Parkinson` disease. J Transl Med. 2015 Dec 21;13:386. doi: 10.1186/s12967-015-0749-9. (SCI, IF=3.786; Medicine, Research & Experimental 30/128)
  • Prognostic impact of renin-angiotensin system blockade in esophageal squamous cell carcinoma. J Renin Angiotensin Aldosterone Syst. 2015 Dec;16(4):1185-92. doi: 10.1177/1470320314535275. Epub 2014 Jun 24. (SCI, IF=1.396; Peripheral Vascular Disease 51/63; corresponding author*)
  • Triple-positive pathologic findings in oral cavity cancer are related to a dismal prognosis. Laryngoscope. 2015 Sep;125(9):E300-5. doi: 10.1002/lary.25463. Epub 2015 Jul 7. (SCI; IF=2.471; Otorhinolaryngology 7/42)
  • Callosal damage and cognitive deficits in chronic carbon monoxide intoxication: A diffusion tensor imaging study. J Neurol Sci. 2015 Aug 15;355(1-2):101-7. doi: 10.1016/j.jns.2015.05.030. Epub 2015 May 28. (SCI; IF=2.295; Clinical neurology 106/194)
  • Long-term neuropsychological sequelae in HIV-seronegative cryptococcal meningoencephalitis patients with and without ventriculoperitoneal shunts: a cine MRI study. Behav Neurol. 2015;2015:356476. doi: 10.1155/2015/356476. Epub 2015 Apr 9. (SCI; IF=1.311; Clinical neurology 159/194)
  • Suppression of Aurora-A-FLJ10540 signaling axis prohibits the malignant state of head and neck cancer. Mol Cancer. 2015 Apr 12;14(1):83 (SCI; IF=6.204; Oncology 31/217)
  • Structural covariance networks of striatum subdivision in patients with Parkinson` disease. Hum Brain Mapp. 2015 Apr;36(4):1567-84 (SCI; IF=4.530; Neuroimaging 2/14)
  • Phosphorylated p70S6K expression is an independent prognosticator for patients with esophageal squamous cell carcinoma. Surgery 2015 Mar;157(3):570-80 (SCI; IF=3.904; Surgery 21/197; first author and corresponding author*)
  • AMACR amplification and overexpression in primary imatinib-naive gastrointestinal stromal tumors: a driver of cell proliferation indicating adverse prognosis. Oncotarget. 2014 Nov 30;5(22):11588-603 (SCI; IF=5.168, Oncology 44/217)
  • Downregulated MTAP expression in myxofibrosarcoma: A characterization of inactivating mechanisms, tumor suppressive function, and therapeutic relevance. Oncotarget. 2014 Nov 30;5(22):11428-41 (SCI; IF=5.168, Oncology 44/217)
  • AMACR amplification in myxofibrosarcomas: a mechanism of overexpression that promotes cell proliferation with therapeutic relevance. Clin Cancer Res. 2014 Dec 1;20(23):6141-52 (SCI; IF=9.619, Oncology 12/217)
  • Longitudinal brain white matter alterations in minimal hepatic encephalopathy before and after liver transplantation. PLoS One. 2014 Aug 28;9(8):e105887 (SCI; IF=2.806; Multidisciplinary sciences 15/64)
  • Interplay between brain stem angiotensins and monocyte chemoattractant protein-1 as a novel mechanism for pressor response after ischemic stroke. Neurobiol Dis. 2014 Nov;71:292-304 (SCI; IF=5.020, NEUROSCIENCES 43/259)
  • Intra-arterial chemotherapy with Doxorubicin and Cisplatin is effective for advanced hepatocellular cell carcinoma. ScientificWorldJournal. 2014;2014:160138 (non-SCI)
  • Diffusion tensor imaging study of white matter damage in chronic meningitis. PLoS One. 2014 Jun 3;9(6):e98210 (SCI; IF=2.806; Multidisciplinary sciences 15/64)
  • Association between Peripheral Oxidative Stress and White Matter Damage in Acute Traumatic Brain Injury. Biomed Res Int. 2014;2014:340936(SCI; IF=2.476 BIOTECHNOLOGY & APPLIED MICROBIOLOGY 67/160)
  • Peripheral leukocyte apoptosis in patients with Parkinsonism: correlation with clinical characteristics and neuroimaging findings. Biomed Res Int. 2014;2014:635923 (SCI; IF=2.476 BIOTECHNOLOGY & APPLIED MICROBIOLOGY 67/160)
  • Addition of the Akt inhibitor triciribine overcomes antibody resistance in cells from ErbB2/Neu-positive/PTEN-deficient mammary tumors. Int J Oncol. 2014 Apr;44(4):1277-83(SCI; IF=3.079; Oncology 105/217)
  • 14-3-3ζ Orchestrates Mammary Tumor Onset and Progression via miR221-Mediated Cell Proliferation. Cancer Res. 2014 Jan 1;74(1):363-73 (SCI; IF=9.122; Oncology 15/217; co-first author)
  • Preoperative chemoradiotherapy followed by surgery in patients with locally advanced esophageal squamous cell carcinoma : A single experience in southern Taiwan. J. Cancer Res. Pract. 2014;1:208-219 (non-SCI)
  • Thymectomy for myasthenia gravis: Video-assisted versus transsternal. Journal of the Formosan medical association. 2014;133:722-726 (SCI ; IF=1.969 ; MEDICINE, GENERAL & INTERNAL 46/155)
  • Post-mastectomy radiotherapy benefits subgroups of breast cancer patients with T1-2 tumor and 1-3 axillary lymph node(s) metastasis. Radiology and oncology. 2014;48:314-322. (SCI ; IF=1.681 ; Radiology, Nuclear medicine & Medical imaging 76/127)
  • Midkine neurite growth-promoting factor 2 expression as a potential prognostic marker of adjuvant therapy in head and neck squamous cell carcinoma. Biomarkers. 2013 Dec;18(8):687-98 (SCI; IF=2.006; Biotechnology & Applied Microbiology 84/160)
  • Structural and cognitive deficits in chronic carbon monoxide intoxication: a voxel-based morphometry study. BMC Neurol. 2013 Oct 1;13(1):129. [Epub ahead of print] (SCI; IF=2.006; Clinical Neurology 124/194)
  • HuR cytoplasmic expression is associated with increased cyclin A expression and inferior disease-free survival in patients with gastrointestinal stromal tumours (GISTs). Histopathology. 2013 Oct;63(4):445-54 (SCI; IF=3.523; Pathology 15/79)
  • ASS1 as a novel tumor suppressor gene in myxofibrosarcomas: aberrant loss via epigenetic DNA methylation confers aggressive phenotypes, negative prognostic impact, and therapeutic relevance. Clin Cancer Res. 2013 Jun 1;19(11) :2861-72. (SCI; IF=9.619, Oncology 12/217)
  • A comparative study of isolated and metachronous oesophageal squamous cell carcinoma with antecedent upper aerodigestive tract cancer. Eur J Cardiothorac Surg. 2013 Nov;44(5):860-5 (SCI; IF=3.759; Surgery 24/196; corresponding author* and co-first author#)
  • Brain metastasis in patients with esophageal squamous cell carcinoma : A single institute experience in southern Taiwan. J. Cancer Res. Pract. 2013;29:182-189 (non-SCI; corresponding author*)
  • Significant volume reduction and shape abnormalities of the basal ganglia in cases of chronic liver cirrhosis. American journal of neuroradiology.2012;33:239-245 (SCI ; IF=3.550 ; RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 22/127)
  • Phosphorylated mammalian target of rapamycin expression is associated with the response to chemoradiotherapy in patients with esophageal squamous cell carcinoma. J Thorac Cardiovasc Surg. 2012 Dec;144(6):1352-1359 (SCI; IF=4.446; Surgery 12/197; first author)
  • Discrepancy between effects of carbapenems and flomoxef in treating nosocomial hemodialysis access-related bacteremia secondary to extended spectrum beta-lactamase producing klebsiella pneumoniae in patients on maintenance hemodialysis. BMC Infectious Diseases 2012, 12:206 (SCI; IF=2.768; Infectious disease 37/84)
  • Concomitant targeting of tumor cells and induction of T cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer. Cancer Res. 2012 Sep 1; 72(17): 4417-28 (SCI; IF=9.122; Oncology 15/217)
  • Comparative Study of Esophageal Stent and Feeding Gastrostomy/Jejunostomy for Tracheoesophageal Fistula Caused by Esophageal Squamous Cell Carcinoma. PLoS ONE 2012, 7(8): e42766 (SCI; IF=2.806; Multidisciplinary sciences 15/64; corresponding author* and co-first author#)
  • Is there a role of whole-body bone scan in patients with esophageal squamous cell carcinoma. BMC Cancer 2012;12:328 (SCI; IF=3.288; Oncology 93/217; first author)
  • Recurrent Amplification at 7q21.2 Targets CDK6 Gene in Primary Myxofibrosarcomas and Identifies CDK6 Overexpression as an Independent Adverse Prognosticator. Ann Surg Oncol. 2012 Aug;19(8):2716-25. (SCI, IF=4.041; Surgery 17/196)
  • Copy number aberrations in combined hepatocellular carcinoma and cholangiocarcinoma. Exp Mol Pathol. 2012 Jun;92(3):281-6 (SCI, IF=2.423; Pathology 25/79)
  • Connectivity of default-mode network is associated with cerebral edema in hepatic encephalopathy. PLoS One. 2012;7(5):e36986. (SCI; IF=2.806; Multidisciplinary sciences 15/64)
  • White matter abnormalities correlating with memory and depression in heroin users under methadone maintenance treatment. PLoS One. 2012;7(4):e33809. (SCI; IF=2.806; Multidisciplinary sciences 15/64)
  • Structural deficits in the emotion circuit and cerebellum are associated with depression, anxiety and cognitive dysfunction in methadone maintenance patients: A voxel-based morphometric study. Psychiatry Res. 2012 Feb 28;201(2):89-97 (SCI, IF=2.528; Psychiatry 65/142)
  • Pre-treatment maximal esophageal wall thickness is independently associated with response to chemoradiotherapy in patients with T3~4 esophageal squamous cell carcinoma. Eur J Cardiothorac Surg. 2012 Dec;42(6):958-64 (SCI, IF=3.759; Surgery 24/196; first author)
  • Characterization of Gene Amplification-Driven SKP2 Overexpression in Myxofibrosarcoma: Potential implications in tumor progression and therapeutics. Clin Cancer Res. 2012 Mar 15;18(6):1598-610 (SCI; IF=9.619, Oncology 12/217)
  • Alpha-methylacyl coenzyme A racemase overexpression in gallbladder carcinoma confers an independent prognostic indicator. J Clin Pathol. 2012 Apr;65(4):309-14 (SCI; IF=2.687; Pathology 22/79)
  • EGFR Nuclear Import in Gallbladder Carcinoma: Nuclear Phosphorylated EGFR Upregulates iNOS Expression and Confers Independent Prognostic Impact. Ann Surg Oncol. 2012 Feb;19(2):443-54. (SCI, IF=4.041; Surgery 17/196)
  • The use of trimodality treatment of locally advanced resectable esophageal squamous cell carcinoma: a single institute experience in southern Taiwan. Journal of Cancer Research and Practice. 2011; Oct 27(5): 200-210 (non-SCI; corresponding author*)
  • The Relationship between Brown Adipose Tissue Activity and Neoplastic Status: an 18F-FDG PET/CT Study in the Tropics. Lipids Health Dis. 2011 Dec 20;10:238 (SCI; IF=2.073; Biochemistry & molecular biology 205/290)
  • Weekly paclitaxel combining with gemcitabine is an effective and safe treatment for advanced breast cancer patients. Jpn J Clin Oncol. 2011 Apr;41(4):455-61 (SCI; IF=1.905; Oncology 164/217)
  • High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area. J Transl Med. 2011 Mar 23;9:31 (SCI, IF=3.786; Medicine, Research & Experimental 30/128)
  • Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways. Nat Med. 2011 Apr;17(4):461-9. (SCI, IF=29.886; Medicine, Research & Experimental 1/128)
  • Prognostic implication of MET overexpression in myxofibrosarcomas: an integrative array comparative genomic hybridization, real-time quantitative PCR, immunoblotting, and immunohistochemical analysis. Mod Pathol. 2010 Oct;23(10):1379-92. (SCI; IF=5.728; Pathology 5/79)
  • Prognostic implication of ezrin overexpression in myxofibrosarcomas. Ann Surg Oncol. 2010 Dec;17(12):3212-9. (SCI, IF=4.041; Surgery 17/196)
  • Upregulation of neutrophil gelatinase-associated lipocalin by ErbB2 through nuclear factor- kappaB activation. Cancer Res. 2009 Dec 15; 69(24): 9163-8. (SCI; IF=9.122; Oncology 15/217; first author)
  • Homozygous Deletion of MTAP gene as a Poor Prognosticator in Gastrointestinal Stromal Tumors. Clinical cancer research 2009 Nov 15;15(22):6963-72. (SCI; IF=9.619, Oncology 12/217)
  • Ezrin overexpression in gastrointestinal stromal tumors: an independent adverse prognosticator associated with the non-gastric location. Mod Pathol. 2009 Oct; 22(10): 1351-60 (SCI; IF=5.728; Pathology 5/79)
  • Higher serum C-reactive protein concentration and hypoalbuminemia are poor prognostic indicators in patients with esophageal cancer undergoing radiotherapy. Radiother Oncol. 2009 Aug;92(2):270-5 (SCI; IF=4.328; Radiology, Nuclear medicine & Medical imaging 14/127; corresponding author*)
  • Concurrent chemoradiotherapy for primary cervical spinal cord germinoma. J Clin Neurosci. 2009 Jan;16(1):115-8 (SCI; IF=1.557; Clinical Neurology 146/194)
  • Upper gastrointestinal bleeding as the initial manifestation of lung adenocarcinoma metastatic to the stomach. Respiratory Medicine Extra 2007; 3: 67-70 (non-SCI; first author)
  • Absence of Epstein-Barr virus in olfactory neuroblastoma. Pathology. 2007 Dec;39(6):565-6. (SCI; IF=2.709; Pathology 21/79)
  • Metastatic Eccrine Porocarcinoma Detected by FDG PET/CT. Clinical Nuclear Medicine 2007;32: 743–5 (SCI; IF=4.563; Radiology, Nuclear medicine & Medical imaging 12/127; first author)
  • Metastatic Urothelial Carcinoma of Upper Urinary Tract. American Journal of Hematology 2007; 82: 940-1 (SCI; IF=5.275; Hematology 14/70; first author)
  • Expression of D2-40 in adjunct diagnosis of papillary thyroid carcinoma. Acta Pathologica, Microbiologica et Immunologica Scandinavica 2007; 115: 906-10 (SCI; IF=1.795; Pathology 43/79)
  • Prognostic Implications of p27 kip1-interacting Cell Cycle Regulators in Gallbladder Carcinoma: a Tissue-microarray-based Immunohistochemical Study of 62 Cases. Mod Pathol. 2007; 20: 497-507 (SCI; IF=5.728; Pathology 5/79; first author)
  • Pseudoaneurysm of the external carotid artery branch following radiotherapy for nasopharyngeal carcinoma. Jpn J Clin Oncol. 2007; 37: 310-3 (SCI; IF=1.905; Oncology 164/217; first author)
  • Expression of human telomerase reverse transcriptase and cyclin-D1 in olfactory neuroblastoma. Acta Pathologica, Microbiologica et Immunologica Scandinavica 2007; 115: 17-21 (SCI; IF=1.795; Pathology 43/79)
  • Immunohistochemical Expression of p16INK4A, Ki-67, and Mcm2 Proteins in Gastrointestinal Stromal Tumors: Prognostic Implications and Correlations with Risk Stratification of NIH Consensus Criteria. Ann Surg Oncol.2006; 13: 1633-44 (SCI, IF=4.041; Surgery 17/196)
  • Incidence of ischemic stroke post-chemotherapy: A retrospective review of 10,963 patients. Clinical Neurology and Neurosurgery 2006; 108: 150–156 (SCI; IF=1.381; Surgery 122/196; first author)
  • Extended Survival in a Patient With Recurrent and Metastatic Adrenal Cortical Carcinoma by Aggressive Transarterial Embolization—a Case Report. Journal of Surgical Oncology 2005; 90: 101–105 (SCI; IF=2.993; Surgery 43/196; first author)
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