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李宗海 醫師

腦血管疾病

教職 : 教授

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語言

  • 國語,英語,閩南語,日語

現職

  • 林口長庚紀念醫院教授級主治醫師

學歷

  • 高雄醫學院醫學系學士
  • 日本東北大學神經內科學醫學博士

經歷

  • 台灣腦中風學會理事長
  • 林口長庚紀念醫院腦血管科主任
  • 林口長庚紀念醫院腦中風中心主任
  • 林口長庚紀念醫院神經內科主治醫師
  • 林口長庚紀念醫院神經內科住院醫師

學會與認證

  • 台灣神經學學會
  • 台灣腦中風學會
  • 中華民國醫用超音波學會
  • 神經科專科醫師證書
  • 神經重症專科醫師證書

論文及期刊發表

  • A Brain-Protective Sterol from Soft Coral Inhibits Lipopolysaccharide-Induced Matrix Metalloproteinase-9-Mediated Astrocytic Migration.
  • Localization of early infarction on non-contrast CT images in acute ischemic stroke with deep learning approach.
  • Early Antiplatelet Resumption and the Risks of Major Bleeding After Intracerebral Hemorrhage.
  • Automatic identification of early ischemic lesions on non?contrast CT with deep learning approach.�
  • Identification of Metabolomics Biomarkers in Extracranial Carotid Artery Stenosis.
  • Mediating roles of leukoaraiosis and infarcts in the effects of unilateral carotid artery stenosis on cognition.
  • Brain Protective Effect of Resveratrol via Ameliorating Interleukin-1-Induced MMP-9-Mediated Disruption of ZO-1 Arranged Integrity.
  • Cognitive Sequelae of Silent Ischemic Lesions Following Carotid Artery Stenting: Possible Role of Age-Related Moderation.
  • Neurodegeneration and Vascular Burden on Cognition After Midlife: A Plasma and Neuroimaging Biomarker Study.
  • Initial in-hospital heart rate is associated with long-term survival in patients with acute ischemic stroke.
  • Induced pluripotent stem cells can improve thrombolytic effect of low?dose rt-PA after acute carotid thrombosis in rat.
  • Total plaque score helps to determine follow-up strategy for carotid artery stenosis progression in head and neck cancer patients after radiation therapy.
  • Hypothyroidism and risks of cerebrovascular complications among patients with head and neck cancer after radiotherapy.
  • Protective effects of ischemic preconditioning against neuronal apoptosis and dendritic injury in the hippocampus are age-dependent.
  • The COX-2-derived PGE 2 autocrine contributes to bradykinin-induced matrix metalloproteinase-9 expression and astrocytic migration via STAT3 signaling.
  • Impact of chronic kidney disease severity on causes of death after first-ever stroke: A population-based study using nationwide data linkage.
  • Investigation of reactive astrogliosis effect on post-stroke cognitive impairment.
  • Maintenance of Stroke Care Quality amid the Coronavirus Disease 2019 Outbreak in Taiwan.
  • Comparison of long-term efficacy and safety between cilostazol and clopidogrel in chronic ischemic stroke: a nationwide cohort study.
  • J Neuroinflammation. 2020 Jun 6;17(1):177. doi: 10.1186/s12974-020-01859-5.
  • Computed Tomography Angiography in Acute Stroke Patients Receiving Recombinant Tissue Plasminogen Activator: Outcome and Safety Evaluations in an Asian Population.
  • Pioglitazone and PPAR-γ modulating treatment in hypertensive and type 2 diabetic patients after ischemic stroke: a national cohort study.
  • Brain computerized tomography reading in suspected acute ischemic stroke patients: what are essentials for medical students?
  • Metabolomics study in severe extracranial carotid artery stenosis.
  • Genomic screening of Fabry disease in young stroke patients: the Taiwan experience and a review of the literature.
  • Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke Patients Receiving Thrombectomy: Standard or Low Dose Therapy?
  • Choices for long-term hypertensive control in patients after first-ever hemorrhagic stroke: a nationwide cohort study.
  • Lipid Paradox in Statin-Naive Acute Ischemic Stroke But Not Hemorrhagic Stroke.
  • The correlation of asymmetrical functional connectivity with cognition and reperfusion in carotid stenosis patients.
  • Causes of Death in Different Subtypes of Ischemic and Hemorrhagic Stroke.
  • Visualization of ischemic stroke-related changes on 18F-THK-5351 positron emission tomography.
  • Changes in E-Selectin Levels Predict Carotid Stenosis Progression after Carotid Artery Stenting.
  • A genome-wide association study links small-vessel ischemic stroke to autophagy.
  • Asymmetric Cerebrovascular Collateral Supply Affects Cognition in Patients with Unilateral Carotid Artery Stenosis.Asymmetric Cerebrovascular Collateral Supply Affects Cognition in Patients with Unilateral Carotid Artery Stenosis.
  • Early-phase 18F-AV-45 PET Imaging can Detect Crossed Cerebellar Diaschisis Following Carotid Artery Stenosis and Cerebral Hypoperfusion.
  • Improved thrombolytic effect with focused ultrasound and neuroprotective agent against acute carotid artery thrombosis in rat.
  • To Load or Not to Load? Aspirin Loading in Acute Ischemic Stroke: A Study of ClinicalOutcomes.
  • The Protective Effect of Human Umbilical Cord Blood CD34+ Cells and Estradiol against Focal Cerebral Ischemia in Female Ovariectomized Rat: Cerebral MR Imaging and Immunohistochemical Study.
  • Identification of PTCSC3 as a Novel Locus for Large-Vessel Ischemic Stroke: A Genome-Wide Association Study.
  • InvestigatorsInitial blood pressure is associated with stroke severity and is predictive of admission cost and one-year outcome in different stroke subtypes: a SRICHS registry study.
  • Graph Theoretical Analysis of Functional Networks and Its Relationship to Cognitive Decline in Patients with Carotid Stenosis.
  • Evaluation of Anti-Infammatory Effects of Helminthostachys zeylanica Extracts viaInhibiting Bradykinin-Induced MMP-9 Expression in Brain Astrocytes.
  • Timing of Symptomatic Infarct Swelling Following Intravenous Thrombolysis in AcuteMiddle Cerebral Artery Infarction: A Case-Control Study.
  • Effect of dehydration on the development of collaterals in acute middle cerebral arteryocclusion .
  • Ezetimibe-Simvastatin Therapy Reduce Recurrent Ischemic Stroke Risks in Type 2Diabetic Patients.
  • Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke.
  • A home-based training programme improves family caregivers' oral care practices with stroke survivors: a randomized controlled trial.
  • Investigating cerebral oedema using poroelasticity.
  • Bladder Dysfunction Induced by Cerebral Hypoperfusion after Bilateral Common Carotid Artery Occlusion in Rats.
  • Carotid Artery Stenting Improves Cerebral Hemodynamics Regardless of the Flow Direction of Ophthalmic Artery.
  • Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis.
  • Recommendations from the international stroke genetics consortium, part2:biological sample collection and storage.
  • Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis.
  • Rationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE study (ENCHANTED) trial: An international multicenter 2 x 2 quasi-factorial randomized controlled trial of low- vs. standard-dose rt-PA and early intensive vs. guideline-recommended blood pressure lowering in patients with acute ischaemic stroke eligible for thrombolysis treatment.
  • Presence of Gyriform Air Predicts Unfavorable Outcome in Venous Catheter-Related Cerebral Air Embolism.
  • Evaluation of Anti-Inflammatory Effects of Helminthostachys zeylanica Extracts via Inhibiting Bradykinin-Induced MMP-9 Expression in Brain Astrocytes.
  • Increased risk of posterior circulation infarcts among ischemic stroke patients with cervical spondylosis.
  • Coexisting diseases of moyamoya vasculopathy.
  • Neuroprotective mechanism of BNG-1 against focal cerebral ischemia: a neuroimaging and neurotrophin study.
  • Impact of Coexisting Coronary Artery Disease on the Occurrence of Cerebral Ischemic Lesions after Carotid Stenting.
  • A Rat Model of Thermbosis in Common Carotid Artery Induced by Implantable Wireless Light-Emitting Diode Device.
  • Perpartion and characterization of biocompatible and thrmoresponsive micells based on poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) grafted on polysuccinimide for drug delivery.
  • Dehydration is an independent predictor of discharge outcome and admission cost in acute ischaemic stroke.
  • Relationships between ophthalmic artery flow direction and cognitive performance in patients with unilateral carotid artery stenosis.
  • Longitudinal MR imaging study in the prediction of ischemic susceptibility after cerebral hypoperfusion in rats: Influence of aging and hypertension.
  • The Reliability and Predictive Ability of a Biomarker of Oxidative DNA Damage on Functional Outcomes after Stroke Rehabilitation.
  • Computer-Aided Diagnosis of Hyperacute Stroke with Thrombolysis Decision Support Using a Contralateral Comparative Method of CT Image Analysis.
  • Genetic Polymorphism of LDLR (rs688) Is Associated with Primary Intracerebral Hemorrhage.
  • Heterogeneous Cerebral Vasoreactivity Dynamics in Patients with Carotid Stenosis.
  • Synthesis and characteristics of biodegradable and temperature responsive polymeric micelles based on poly(aspartic acid) -g-poly (N-isopropylacrylamide-co-N ,N-dimethylacrylamide).
  • Less favorable neurological recovery after acute stroke in patients with hypercholesterolemia.
  • Rapid progression and brain atrophy in anti-AMPA receptor encephalitis.
  • Effects of sex hormones on cell proliferation and apoptosis in the urinary bladder muscle of ovariectomized rat.
  • Fire-heat and Qi deficiency syndromes as predictors of short-term prognosis of acute ischemic stroke.
  • Differential trajectory of functional recovery and determinants for first time stroke survivors by using a LCGA approach: a hospital based analysis over a 1-year period.
  • The Impact Factors on the Cost and Length of Stay among Acute Ischemic Stroke.
  • The impact of intracranial carotid artery calcification on the development of thrombolysis-induced intracerebral hemorrhage.
  • Brain computed tomography perfusion may help to detect hemodynamic reconstitution and predict intracerebral hemorrhage after carotid stenting.
  • Amyloid deposition after cerebral hypoperfusion: Evidenced on [(18)F]AV-45 positron emission tomography.
  • Cervicocranial Fibromuscular Dysplasia in Taiwanese Ischemic Stroke Patients.
  • Predictors of clinical deterioration during hospitalization following acute ischemic stroke.
  • Symptomatic pulmonary embolism among stroke patients in Taiwan: a retrospective cohort study.
  • Cost-effectiveness analysis of stroke management under a universal health insurance system.
  • Polymorphisms at the LDLR Locus may be Associated with Ischemic Cerebrovascular Disease Independent of Lipid Profile.
  • Paraoxonase-1 is not a major determinant of stent thrombosis in a Taiwanese population.
  • Bronchorrhea following Stroke.
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