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陳妙芬

長庚醫院學術組教授級主治醫師

放射腫瘤科

食道癌、乳癌、泌尿道癌、肺癌之光子與質子治療、立體定位放射治療、輻射生物基礎及轉譯研究

教職 : 教授

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語言

  • 國語,英語,閩南語

現職

  • 長庚醫院學術組教授級主治醫師
  • 長庚大學部定教授

學歷

  • 長庚大學臨床醫學研究所博士
  • 台北醫學院醫學系

經歷

  • 2014~   長庚大學部定教授
  • 2013~   長庚醫院放射腫瘤科教授級主治醫師
  • 2011~2014 長庚大學專任副教授
  • 2010~2013 長庚醫院放射腫瘤科副教授級主治醫師
  • 2008~2011 長庚大學專任助理教授
  • 2007~2010 長庚醫院放射腫瘤科助理教授級主治醫師

學會與認證

  • 台灣放射腫瘤學會

論文及期刊發表

  • Role of vitamin D3 in tumor aggressiveness and radiation response for hepatocellular carcinoma.
  • Prospective Evaluation of Taste Function in Patients With Head and Neck Cancer Receiving Intensity-Modulated Radiotherapy.
  • Effect of 1α,25-Dihydroxyvitamin D3 on the Radiation Response in Prostate Cancer: Association With IL-6 Signaling.
  • Role of Nutritional Status in the Treatment Outcome for Esophageal Squamous Cell Carcinoma.
  • Intracavernous Injection of Autologous Platelet-Rich Plasma Ameliorates Hyperlipidemia-Associated Erectile Dysfunction in a Rat Model.
  • Risk of major adverse cardiovascular events among second-line hormonal therapy for metastatic castration-resistant prostate cancer: A real-world evidence study.
  • Survival of Patients with Lung Cancer in the Setting of Liver Cirrhosis: A Multicenter Propensity Score Matching Study.
  • Survival-Weighted Health Profiles in Nasopharyngeal Cancer Patients.
  • A Retrospective Analysis of Dose Distribution and Toxicity in Patients with Left Breast Cancer Treated with Adjuvant Intensity-Modulated Radiotherapy: Comparison with Three-Dimensional Conformal Radiotherapy.
  • Prognostic Significance of Neoadjuvant Rectal Scores in Preoperative Short-Course Radiotherapy and Long-Course Concurrent Chemoradiotherapy for Patients with Locally Advanced Rectal Cancer.
  • Porphyromonas gingivalis promotes tumor progression in esophageal squamous cell carcinoma.
  • The Predictive Role of Prostate-Specific Antigen Changes Following Transurethral Resection of the Prostate for Patients with Localized Prostate Cancer.
  • The Significance of Neutrophil-to-Lymphocyte Ratio and Combined Chemoradiotherapy in Patients Undergoing Bladder Preservation Therapy for Muscle-Invasive Bladder Cancer.
  • Prognostic Significance of Neoadjuvant Rectal Scores in Preoperative Short-Course Radiotherapy and Long-Course Concurrent Chemoradiotherapy for Patients with Locally Advanced Rectal Cancer.
  • Effect of Tumor Burden on Tumor Aggressiveness and Immune Modulation in Prostate Cancer: Association with IL-6 Signaling.
  • Long-Term Taste Impairment after Intensity-Modulated Radiotherapy to Treat Head-and-Neck Cancer: Correlations with Glossectomy and the Mean Radiation Dose to the Oral Cavity.
  • The prognosis of head and neck squamous cell carcinoma related to immunosuppressive tumor microenvironment regulated by IL-6 signaling.
  • Lung cancer outcome in the setting of chronic kidney disease: Does the glomerular filtration estimation formula matter?
  • The Response of Prostate Cancer to Androgen Deprivation and Irradiation Due to Immune Modulation.
  • The Predictive Value of Pretreatment Neutrophil-To-Lymphocyte Ratio in Esophageal Squamous Cell Carcinoma.
  • Predictive Value of the Pretreatment Neutrophil-to-Lymphocyte Ratio in Head and Neck Squamous Cell Carcinoma.
  • Predictive Value of CD44 in Muscle-Invasive Bladder Cancer and Its Relationship with IL-6 Signaling.
  • Cell Subpopulations Overexpressing p75NTR Have Tumor-initiating Properties in the C6 Glioma Cell Line.
  • Epigenetic therapy regulates the expression of ALDH1 and immunologic response: Relevance to the prognosis of oral cancer.
  • Cystectomy for bladder cancer in elderly patients is not associated with increased 30- and 90-day mortality or readmission, length of stay, and cost: propensity score matching using a population database.
  • Role of ALDH1 in the prognosis of esophageal cancer and its relationship with tumor microenvironment.
  • Survival benefit of surgery to patients with esophageal squamous cell carcinoma.
  • Impact of CD44 expression on radiation response for bladder cancer.
  • Inflammation-induced myeloid-derived suppressor cells associated with squamous cell carcinoma of the head and neck.
  • Is chronic kidney disease an adverse factor in lung cancer clinical outcome? A propensity score matching study.
  • To Operate or Not: Prediction of 3-Month Postoperative Mortality in Geriatric Cancer Patients.
  • he role of PD-L1 in the radiation response and prognosis for esophageal squamous cell carcinoma related to IL-6 and T-cell immunosuppression.
  • The role of PD-L1 in the radiation response and clinical outcome for bladder cancer.
  • Identification of High-Risk Subgroups of Patients With Oral Cavity Cancer in Need of Postoperative Adjuvant Radiotherapy or Chemo-Radiotherapy.
  • 1α,25- Dihydroxyvitamin D3 Inhibits Esophageal Squamous Cell Carcinoma Progression by Reducing IL6 Signaling.
  • Androgen deprivation increases the risk of fracture in prostate cancer patients: a population-based study in Chinese patients.
  • The Efficacy of Postoperative Adjuvant Chemotherapy for Patients with pT3N0M0 Upper Tract Urothelial Carcinoma.
  • A simple risk stratification model that predicts 1-year postoperative mortality rate in patients with solid-organ cancer.
  • TGF Beta1 Expression Correlates with Survival and Tumor Aggressiveness of Prostate Cancer.
  • A simple risk stratification model that predicts 1-year postoperative mortality rate in patients with solid-organ cancer.
  • Significance of DNMT3b in oral cancer.
  • Thrombomodulin expression regulates tumorigenesis in bladder cancer.
  • stimation of life expectancy and quality-adjusted life expectancy in non-metastatic nasopharyngeal cancer patients treated by intensity-modulated radiotherapy with or without chemotherapy.
  • TGF-β1 mediates the radiation response of prostate cancer.
  • IL-6-stimulated CD11b+ CD14+ HLA-DR- myeloid-derived suppressor cells, are associated with progression and poor prognosis in squamous cell carcinoma of the esophagus.
  • Clinical characteristics and treatment outcome in a Taiwanese population of patients with Epstein-Barr virus-positive diffuse large B-cell lymphoma.
  • The role of IL-6 in the radiation response of prostate cancer.
  • Outcome of patients with esophageal cancer: a nationwide analysis.
  • IL-6 expression regulates tumorigenicity and correlates with prognosis in bladder cancer.
  • Scintigraphic assessment of salivary function after intensity-modulated radiotherapy for head and neck cancer: Correlations with parotid dose and quality of life.
  • Role of Interleukin-6 in the Radiation Response of Liver Tumors.
  • Detection of Mucosal Recurrent Nasopharyngeal Carcinomas after Radiotherapy with Narrow-Band Imaging Endoscopy.
  • Role of DNA methyltransferase 3b in esophageal squamous cell carcinoma.
  • Significance of IL-6 in the transition of hormone-resistance prostate cancer and the induction of myeloid derived suppressor cells .
  • Comparison of treatment results between surgery alone, preoperative short-course radiotherapy, or long-course concurrent chemoradiotherapy in locally advanced rectal cancer.
  • Significance of the TGF-beta1-IL-6 axis in oral cancer.
  • Role of DNA methyltransferase 3b in esophageal squamous cell carcinoma.
  • Significance of IL-6 in the transition of hormone-resistance prostate cancer and the induction of myeloid derived suppressor cells .
  • Expression and function role of DNA methyltransferase 1 in human bladder cancer.
  • CK2 inhibitors enhance the radiosensitivity of human non-small cell lung cancer cells through inhibition of stat3 activation.
  • Incidence and Patterns of Second Primary Malignancies Following Oral Cavity Cancers in a Prevalent Area of Betel-nut Chewing: A Population-based Cohort of 26 166 Patients in Taiwan.
  • Significance of IL-6 signaling in pharyngeal cancer in its resistance to irradiation and the EGFR inhibitor.
  • The role of peroxiredoxin I in rectal cancer and related to p53 status.
  • Predictive factors of radiation-induced skin toxicity in breast cancer patients.
  • Role of DNA methyltransferase 1 in hormone-resistant prostate cancer .
  • Inhibition of corneal neovascularization with plasmid pigment epithelium-derived factor (p-PEDF) delivered by synthetic amphiphile INTeraction-18 (SAINT-18) vector in an experimental model of rat corneal angiogenesis.
  • Adenovirus-mediated transfer of siRNA against survivin enhances the radiosensitivity of human non-small cell lung cancer cells.
  • Comparison between pre-operative short course radiotherapy and long course chemoradiotherapy in patients with locally advanced rectal cancers.
  • Androgen deprivation modulates the inflammatory response induced by irradiation.
  • The predictive role of E2-EPF ubiquitin carrier protein in esophageal squamous cell carcinoma.
  • Significance of nuclear accumulation of Foxo3a in esophageal squamous cell carcinoma.
  • Adjuvant concurrent chemoradiotherapy with intensity-modulated pelvic radiotherapy after surgery for high-risk, early stage cervical cancer patients.
  • Clinical outcome in post-hysterectomy cervical cancer patients treated with concurrent cisplatin and intensity-modulated pelvic radiotherapy: comparison with conventional radiotherapy.
  • The radiation response for hormone- resistant prostate cancer induced by long- term hormone therapy.
  • Predictive role of nuclear factor-κB activity in gastric cancer: A promising adjuvant approach with caffeic acid phenethyl ester.
  • Inhibition of lung tumor growth and augmentation of radiosensitivity by decreasing peroxiredoxin I expression.
  • The sensitivity of human mesenchymal stem cells to ionizing radiation.
  • P53 status is a major determinant of the effects of decreasing peroxiredoxin I expression on tumor growth and response of lung cancer cells to treatment.
  • Differential effects of caffeic acid phenethyl ester for normal lung and lung cancer treated with irradiation: in vitro and in vivo study.
  • Prediction of poor survival by cyclooxygenase-2 in patients with T4 nasopharyngeal cancer treated by radiation therapy: clinical and in vitro studies.
  • Cell killing and radiosensitization by caffeic acid phenethyl ester (CAPE) in lung cancer cells.
  • The role of radiotherapy in the treatment of early stage glottic cancer.
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